3411-09-4

Basic information

• Product Name: 4-(2,6-Dimethoxy-4-pentylphenyl)-3-buten-2-one
• Synonyms: 4-(2,6-Dimethoxy-4-pentylphenyl)-3-buten-2-one
• CAS NO: 3411-09-4
• Molecular Formula: C₁₇H₂₄O₃
• Molecular Weight: 0
• Mol File: 3411-09-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 417.7°C at 760 mmHg
• Flash Point: 198.2°C
• Appearance: /
• Density: 1.007g/cm³
• Vapor Pressure: 3.46E-07mmHg at 25°C
• Refractive Index: 1.521
• CAS DataBase Reference: 4-(2,6-Dimethoxy-4-pentylphenyl)-3-buten-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2,6-Dimethoxy-4-pentylphenyl)-3-buten-2-one(3411-09-4)
• EPA Substance Registry System: 4-(2,6-Dimethoxy-4-pentylphenyl)-3-buten-2-one(3411-09-4)

Safety Data

• Hazardous Substances Data: 3411-09-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C17H24O3/c1-5-6-7-8-14-11-16(19-3)15(10-9-13(2)18)17(12-14)20-4/h9-12H,5-8H2,1-4H3/b10-9+

Upstream product

• 3410-84-2 2,6-dimethoxy-4-pentylbenzaldehyde 
• 67-64-1 acetone 
• 500-66-3 Olivetol 
• 22976-40-5 1,3-dimethoxy-5-pentylbenzene 

Downstream Products

• 7663-54-9 1-(2',6'-Dimethoxy-4'-n-pentylphenyl)-3-methyl-butadien 
• 3411-08-3 2',6'-Dimethoxy-4'-pentyl-3-methyl-6-acetyl-1,2,5,6-tetrahydro-biphenyl 
• 1242-66-6 2',6'-Dimethoxy-4'-pentyl-3-methyl-6-isopropyl-1,2,3,4,5,6-hexahydrobiphenyl 
• 3410-79-5 2',6'-Dimethoxy-4'-pentyl-3-methyl-6-isopropylen-1,2,5,6-tetrahydro-biphenyl 
• 3556-78-3 cis-DL-Cannabidiol 
• 3556-78-3 trans-4-[3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-1,3-benzenediol 
• 1242-67-7 1,3-dimethoxy-2-((1RS,6RS)-3-methyl-6-(prop-1-en-2-yl)cyclohex-2-enyl)-5-pentylbenzene 
• 930597-95-8 methyl (1R,2R)-2',6'-dimethoxy-5-methyl-4'-pentyl-1,2,3,4-tetrahydro-[1,1'-biphenyl]-2-carboxylate 
• 1972-08-3 dronabinol 
• 1310045-84-1 1-(2',6'-dimethoxy-5-methyl-4'-pentyl-1,2,3,4-tetrahydro-[1,1'-biphenyl]-2-yl)ethanone 
• 1242-67-7 O-2797 
• 1972-05-0 Cannabidiol monomethyl ether 

Relevant articles and documents

SYNTHESIS OF CANNABINOIDS

Provided are synthesis processes and intermediates for preparing cannabinoids and analogs.

High-pressure access to the Δ9-cis - And Δ9-trans-tetrahydrocannabinols family

Diels-Alder reactions of a range of 1-(alkoxy/alkyl-substituted phenyl)buta-1,3-dienes with methyl vinyl ketone and methyl acrylate carried out in ethanol as the reaction medium under 9 kbar pressure were investigated. The use of high pressure as the activating method of the Diels-Alder reactions allows the efficient and endodiastereoselective generation of a series of cis-cyclohexenyl-benzene cycloadducts, which are selectively converted into their trans-epimers. The cis-cyclohexenyl-benzenes and trans-cyclohexenyl- benzenes produced are useful precursors for accessing substituted privileged cis-6a,7,8,10a-tetrahydro-6H-benzo[c]chromene and trans-6a,7,8,10a-tetrahydro- 6H-benzo[c]chromene skeletons. The total syntheses of Δ9-cis- tetrahydrocannabinol (THC) and Δ9-trans-THC, through the use of selected Diels-Alder adducts, are described. Finally, a route for obtaining Δ9-trans-THC in both enantiomeric pure forms based on the (S)-(-)-1-amino-2-(methoxymethyl)pyrrolidine (SAMP)-hydrazone method is also reported.