342603-80-9Relevant articles and documents
Implications for selectivity of 3,4-diarylquinolinones as p38αMAP kinase inhibitors
Peifer, Christian,Urich, Robert,Schattel, Verena,Abadleh, Mohammed,Roettig, Marc,Kohlbacher, Oliver,Laufer, Stefan
, p. 1431 - 1435 (2008/12/21)
In this study we report on the specificity profiling of the MAP kinase inhibitors 1, 2, and 3 in a panel of 78 protein kinases including the MAPK isoforms p38(α,β,γ,δ), JNK1/2/3, and ERK1/2/8 showing 3-(4-fluorophenyl)-4-pyridin-4-ylquinolin-2(1H)-one (1)