343798-56-1

Basic information

• Product Name: 1,3-bis(4-(tert-butyl)phenyl)prop-2-yn-1-one
• Synonyms: 1,3-bis(4-(tert-butyl)phenyl)prop-2-yn-1-one
• CAS NO: 343798-56-1
• Molecular Weight: 318.459
• Mol File: 343798-56-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,3-bis(4-(tert-butyl)phenyl)prop-2-yn-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-bis(4-(tert-butyl)phenyl)prop-2-yn-1-one(343798-56-1)
• EPA Substance Registry System: 1,3-bis(4-(tert-butyl)phenyl)prop-2-yn-1-one(343798-56-1)

Safety Data

• Hazardous Substances Data: 343798-56-1(Hazardous Substances Data)

Upstream product

• 98-73-7 4-(1,1-dimethylethyl)benzoic acid 
• 201230-82-2 carbon monoxide 
• 35779-04-5 1-tert-butyl-4-iodobenzene 
• 772-38-3 4-tert-Butylphenylacetylene 
• 1710-98-1 p-tert-butyl benzoyl chloride 

Relevant articles and documents

Nickel catalysed carbonylative Sonogashira reaction for the synthesis of diarylalkynones and 2-substituted flavones

The nickel catalyzed, palladium/phosphine free carbonylative Sonogashira reaction of terminal alkynes with substituted aryl and heteroaryl iodides is described. This protocol provides mild and robust conditions to synthesize a variety of substituted aryl α,β-alkynyl ketones and flavones in good to excellent isolated yields. This methodology tolerates several functional groups such as electron donating (methyl, isopropyl, tert-butyl, methoxy) as well as electron withdrawing (trifluoromethyl, nitro, esters, nitrile) groups on the terminal alkynes and iodides.

Oxidation of aromatic compounds: VII oxidation of symmetrically substituted 1,3-diarylpropynones in the system CF3COOH-CH2Cl2-PbO2. New synthesis method of 1,1,2,2-tetraaroylethenes

Preparative oxidation of 1,3-diarypropynones ArC≡CCOAr in a system CF3COOH-CH2Cl2-PbO2 at 18-20°C within 1.5-25 h results in 1,1,2,2-tetraaroylethenes (ArCO)2C= C(COAr)2 in yields up to 75%. The most easily and efficiently the products form from the substrates where the aryl moiety conjugated with the triple bond contains electron-donating substituents p-MeO, p-Me, and p-t-Bu. On heating with hydrazine 1,1,2,2-tetrakis(4-methoxyphenylcarbonyl)ethene is converted into heterocyclic structures: pyridazine and 2,3,6,7-tetraazanaphthalene derivatives.