343830-62-6

Basic information

• Product Name: 2H-Indol-2-one, 1,3-dihydro-1-(phenylmethyl)-3-(phenylmethylene)-
• CAS NO: 343830-62-6
• Molecular Formula: C22H17NO
• Molecular Weight: 311.383
• Mol File: 343830-62-6.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2H-Indol-2-one, 1,3-dihydro-1-(phenylmethyl)-3-(phenylmethylene)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Indol-2-one, 1,3-dihydro-1-(phenylmethyl)-3-(phenylmethylene)-(343830-62-6)
• EPA Substance Registry System: 2H-Indol-2-one, 1,3-dihydro-1-(phenylmethyl)-3-(phenylmethylene)-(343830-62-6)

Safety Data

• Hazardous Substances Data: 343830-62-6(Hazardous Substances Data)

Upstream product

• 3359-49-7 3-benzylideneoxindole 
• 100-39-0 benzyl bromide 
• 1217-89-6 1-benzylisatin 
• 91-56-5 indole-2,3-dione 
• 7135-32-2 1-benzylindolin-2-one 
• 100-52-7 benzaldehyde 
• 59-48-3 2-oxoindole 
• 98-80-6 phenylboronic acid 
• 753451-40-0 N-benzyl-N-(2-iodophenyl)propiolamide 

Relevant articles and documents

A convenient synthesis of (E)-α-alkylidene-γ-lactams and (E)-3-alkylideneoxindoles by rhodium-catalyzed intramolecular hydroamidation

Rhodium-catalyzed carbonylative cyclization without carbon monoxide was investigated. Cyclization of various formamides having alkynyl groups proceeded smoothly in the presence of Rh4(CO)12 to provide α-alkylidene-γ-lactams or 3-alky

Candida antarctica lipase-B-catalyzed kinetic resolution of 1,3-dialkyl-3-hydroxymethyl oxindoles

Candida antarctica (CAL-B) lipase-catalyzed resolution of 1,3-dialkyl-3-hydroxymethyl oxindoles has been performed to obtain (R)-1,3-dialkyl-3-acetoxymethyl oxindoles with up to 99% ee and (S)-1,3-dialkyl-3-hydroxymethyl oxindoles with up to 78% ee using vinyl acetate as acylating agent and acetonitrile as solvent transforming (S)-3-allyl-3-hydroxymethyl oxindole to (3S)-1′-benzyl-5-(iodomethyl)-4,5-dihydro-2H-spiro[furan-3,3′-indolin]-2′-one. The optically active 3-substituted-3-hydroxymethyl oxindoles and spiro-oxindoles are among the key synthons in the synthesis of potentially biologically active molecules.

Molybdenum-catalyzed asymmetric allylic alkylation of 3-alkyloxindoles: Reaction development and applications

We report a full account of our work towards the development of Mo-catalyzed asymmetric allylic alkylation reactions with 3-alkyloxindoles as nucleophiles. The reaction is complementary to the Pd-catalyzed reaction with regard to the scope of oxindole nucleophiles. A number of 3-alkyloxindoles were alkylated successfully under mild conditions to give products with excellent yields and good-to-excellent enantioselectivities. Applications of this method to the preparation of indoline alkaloids such as (-)-physostigmine, ent-(-)-debromoflustramine B, and the indolinoquinoline rings of communesin B are reported.