344-29-6

Basic information

• Product Name: 2-AMINO-5-FLUORO-3-NITROBENZOTRIFLUORIDE
• Synonyms: 2-AMINO-5-FLUORO-3-NITROBENZOTRIFLUORIDE;4-fluoro-2-nitro-6-(trifluoromethyl)Benzenamine;2-Amino-5-fluoro-3-nitrobenzotrifluoride97%;4-Fluoro-2-nitro-6-(trifluoromethyl)aniline
• CAS NO: 344-29-6
• Molecular Formula: C₇H₄F₄N₂O₂
• Molecular Weight: 224.11
• Mol File: 344-29-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 261.6°Cat760mmHg
• Flash Point: 112°C
• Appearance: /
• Density: 1.586g/cm³
• Vapor Pressure: 0.0114mmHg at 25°C
• Refractive Index: 1.506
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: -2.82±0.25(Predicted)
• CAS DataBase Reference: 2-AMINO-5-FLUORO-3-NITROBENZOTRIFLUORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-5-FLUORO-3-NITROBENZOTRIFLUORIDE(344-29-6)
• EPA Substance Registry System: 2-AMINO-5-FLUORO-3-NITROBENZOTRIFLUORIDE(344-29-6)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 344-29-6(Hazardous Substances Data)

Usage

Description

2-AMINO-5-FLUORO-3-NITROBENZOTRIFLUORIDE is a chemical compound that belongs to the class of substituted benzotrifluorides. It is characterized by the presence of an amino group, a fluorine atom, and a nitro group attached to a benzene ring, with three trifluoromethyl groups attached to it. This unique structure makes it a valuable research intermediate in the development of various chemical and pharmaceutical applications.

Uses

Used in Research and Development:
2-AMINO-5-FLUORO-3-NITROBENZOTRIFLUORIDE is used as a research intermediate for the synthesis of various organic compounds and pharmaceuticals. Its unique structure allows for the development of new chemical entities with potential applications in various industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-AMINO-5-FLUORO-3-NITROBENZOTRIFLUORIDE is used as a key intermediate in the synthesis of drug candidates. Its versatile chemical properties enable the development of new drugs with improved therapeutic effects and reduced side effects.
Used in Chemical Industry:
2-AMINO-5-FLUORO-3-NITROBENZOTRIFLUORIDE is also used in the chemical industry for the production of various specialty chemicals, such as dyes, pigments, and agrochemicals. Its unique structure and reactivity make it a valuable building block for the synthesis of these compounds.

InChI:InChI=1/C7H4F4N2O2/c8-3-1-4(7(9,10)11)6(12)5(2-3)13(14)15/h1-2H,12H2

Upstream product

• 389-75-3 acetic acid-(4-fluoro-2-nitro-6-trifluoromethyl-anilide) 
• 393-39-5 4-fluoro-2-(trifluoromethyl)aniline 
• 393-23-7 N-(4-fluoro-2-(trifluoromethyl)phenyl)acetamide 

Downstream Products

• 440-68-6 7-fluoro-2,3-diphenyl-5-trifluoromethyl-quinoxaline 
• 179062-02-3 2,3-diamino-5-fluorobenzotrifluoride 
• 15804-19-0 quinoxaline-2,3-dione 

Relevant articles and documents

Glycine receptor antagonists and the use thereof

Methods of treating or preventing neuronal loss associated with stroke, ischemia, CNS trauma, hypoglycemia and surgery, as well as treating neurodegenerative diseases including Alzheimer's disease, amyotrophic lateral sclerosis, Huntington's disease and Down's syndrome, treating or preventing the adverse consequences of the hyperactivity of the excitatory amino acids, as well as treating anxiety, chronic pain, convulsions, inducing anesthesia and treating psychosis are disclosed by administering to an animal in need of such treatment a compound having high affinity for the glycine binding site, lacking PCP side effects and which crosses the blood brain barrier of the animal. Also disclosed are novel 1,4-dihydroquinoxaline-2,3-diones, and pharmaceutical compositions thereof. Also disclosed are highly soluble ammonium salts of 1,4-dihydroquinoxaline-2,3-diones.