34665-81-1Relevant articles and documents
Controlling Chemoselectivity of Catalytic Hydroboration with Light
Bergamaschi, Enrico,Chen, Yi-Kai,Hohenadel, Melissa,Lunic, Danijela,McLean, Liam A.,Teskey, Christopher J.
, (2022/01/13)
The ability to selectively react one functional group in the presence of another underpins efficient reaction sequences. Despite many designer catalytic systems being reported for hydroboration reactions, which allow introduction of a functional handle fo
Catalytic, Enantioselective Vinylogous Mukaiyama Aldol Reaction of Furan-Based Dienoxy Silanes: A Chemodivergent Approach to γ-Valerolactone Flavan-3-ol Metabolites and δ-Lactone Analogues
Curti, Claudio,Brindani, Nicoletta,Battistini, Lucia,Sartori, Andrea,Pelosi, Giorgio,Mena, Pedro,Brighenti, Furio,Zanardi, Franca,Delrio, Daniele
supporting information, p. 4082 - 4092 (2016/01/25)
The asymmetric synthesis of a set of hydroxyphenyl γ-valerolactones was achieved starting from 2-silyloxyfuran and alkoxy-substituted benzaldehydes as common precursors. Key synthesis steps included an enantioselective vinylogous Mukaiyama aldol reaction and a Barton-McCombie deoxygenation. Five enantioenriched γ-valerolactone targets were obtained in 5-6 steps, 18-63% overall yields and 82-98 % ee, paving the way for the straightforward entry to this class of biologically effective and poorly available flavan-3-ol metabolites. In parallel, an unprecedented one-pot reductive ring expansion process was fortuitously discovered, yielding racemic δ-lactone analogues from phenolic butanolide precursors.
THE SYNTHESIS VIA ORGANOIRON COMPLEXES OF PEDICELLANIN METHYL ETHER AND CUPARENE
Bovicelli, P,Mincione, E.
, p. 2037 - 2050 (2007/10/02)
A synthetic route to Pedicellanin methyl ether as well as to Cuparene via iron tricarbonyl-cyclohexadienyl cations is reported.The unusual aromatization reaction of the iron tricarbonyl- cyclohexadienyl mojety by iron trichloride is evidencied.
