346700-35-4

Basic information

• Product Name: 4-((E)-2-{4-[7-Bromo-2-(4-bromo-but-2-ynyl)-hept-5-ynyloxy]-phenyl}-1-ethyl-but-1-enyl)-phenol
• Synonyms: 4-((E)-2-{4-[7-Bromo-2-(4-bromo-but-2-ynyl)-hept-5-ynyloxy]-phenyl}-1-ethyl-but-1-enyl)-phenol
• CAS NO: 346700-35-4
• Molecular Weight: 572.38
• Mol File: 346700-35-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-((E)-2-{4-[7-Bromo-2-(4-bromo-but-2-ynyl)-hept-5-ynyloxy]-phenyl}-1-ethyl-but-1-enyl)-phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-((E)-2-{4-[7-Bromo-2-(4-bromo-but-2-ynyl)-hept-5-ynyloxy]-phenyl}-1-ethyl-but-1-enyl)-phenol(346700-35-4)
• EPA Substance Registry System: 4-((E)-2-{4-[7-Bromo-2-(4-bromo-but-2-ynyl)-hept-5-ynyloxy]-phenyl}-1-ethyl-but-1-enyl)-phenol(346700-35-4)

Safety Data

• Hazardous Substances Data: 346700-35-4(Hazardous Substances Data)

Upstream product

• 178432-52-5 1,10-bis(tetrahydropyranyloxy)-5-hydroxymethyl-2,8-decadiyne 
• 263720-92-9 1,10-dihydroxy-5-tert-butyldimethylsiloxymethyl-2,8-decadiyne 
• 346700-32-1 5-(O-diethylstilbestrol phenoxymethyl)-2,8-decadiyne-1,10-diol 

Downstream Products

• 346700-29-6 1,10-dibromo-5-(O-diethylstilbestryl-[O-tertbutyldimethylsilyl] phenoxymethyl)-2,8-decadiyne 
• 178432-55-8 1,10-dibromo-5-(O-diethylstilbestryl-[O-methyl] phenoxymethyl)-2,8-decadiyne 

Relevant articles and documents

Target-directed enediynes: Designed estramycins

The goal of selective targeting of enediyne cytotoxins has been investigated using estrogenic delivery vehicles. A series of estrogen-enediyne conjugates were assembled, and affinity for human estrogen receptor [hERα] was determined. The most promising candidate induced receptor degradation following Bergman cycloaromatization and caused inhibition of estrogen-induced transcription in T47-D human breast cancer cells.