348-35-6

Basic information

• Product Name: 2-(4-Fluorophenyl)-5-nitrobenziMidazole, 95%
• Synonyms: 2-(4-Fluorophenyl)-5-nitrobenziMidazole, 95%;2-(4-Fluoro-phenyl)-5-nitro-1H-benzoimidazole
• CAS NO: 348-35-6
• Molecular Formula: C₁₃H₈FN₃O₂
• Molecular Weight: 257.2199232
• Mol File: 348-35-6.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(4-Fluorophenyl)-5-nitrobenziMidazole, 95%(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Fluorophenyl)-5-nitrobenziMidazole, 95%(348-35-6)
• EPA Substance Registry System: 2-(4-Fluorophenyl)-5-nitrobenziMidazole, 95%(348-35-6)

Safety Data

• Hazardous Substances Data: 348-35-6(Hazardous Substances Data)

Usage

General Description

2-(4-Fluorophenyl)-5-nitrobenzimidazole, 95% is a chemical compound that is primarily composed of 2-(4-Fluorophenyl)-5-nitrobenzimidazole in a 95% purity level. 2-(4-Fluorophenyl)-5-nitrobenziMidazole, 95% is a derivative of benzimidazole and contains a nitro group and a fluorophenyl group. It is commonly used as a pharmaceutical intermediate in the production of various medications. The 95% purity level indicates that the compound is highly concentrated and suitable for use in research and manufacturing processes where a high level of purity is required. It is important to handle and store this chemical compound with care due to its potentially hazardous nature.

Upstream product

• 459-57-4 4-fluorobenzaldehyde 
• 99-56-9 4-Nitrophenylene-1,2-diamine 

Downstream Products

• 863869-96-9 2-(4-fluorophenyl)-1H-benzo[d]imidazole-5-amine 
• 1223478-11-2 N-(2-(4-fluorophenyl)-1H-benzo[d]imidazol-5-yl)-5-methyl pyrazine-2-carboxamide 
• 1241617-48-0 N-(2-(4-fluorophenyl)-1H-benzo[d]imidazol-5-yl)pyrazine-2-carboxamide 
• 1440142-05-1 C₂₀H₁₄FN₃O 
• 1372128-51-2 C₂₀H₁₃FN₄O₃ 
• 1440142-11-9 C₂₀H₁₃ClFN₃O 
• 1440142-14-2 C₂₁H₁₆FN₃O₂ 
• 1593834-60-6 N-(2-(4-fluorophenyl)-1H-benzo[d]imidazol-6-yl)quinolin-4-amine 

Relevant articles and documents

Highly chemoselective synthesis of benzimidazoles in Sc(OTf)3-catalyzed system

The present researches elicit a simple, green and efficient method for the synthesis of substituted benzimidazoles through the coupling of o-phenylenediames with aldehydes catalyzed by Sc(OTf)3 in ethanol, which obtains high chemoselectivity and excellent yield of many biologically active 1,2-disubstitued and 2-substituted benzimidazoles respectively and are also environment friendly.

Discovery of benzimidazole derivatives as novel multi-target EGFR, VEGFR-2 and PDGFR kinase inhibitors

Multi-target EGFR, VEGFR-2 and PDGFR inhibitors are highly useful anticancer agents with improved therapeutic efficacies. In this work, we used two virtual screening methods, support vector machines (SVM) and molecular docking, to identify a novel series

H2O2/Fe(NO3)3-promoted synthesis of 2-arylbenzimidazoles and 2-arylbenzothiazoles

A new, convenient synthesis of 2-substituted benzimidazoles and benzothiazoles is described. Short reaction time, easy and quick isolation of the products, environmentally friendly procedure, excellent chemoselectivity and excellent yields are main advantages of this procedure. Georg Thieme Verlag Stuttgart.