34927-45-2 Usage
Description
5C-aglycone, also known as 2-Methyl-3-(3''-carboxybutyl)-1,4-naphthoquinone, is a metabolite of Vitamin K2, specifically MK-4 (M218595). It is recognized for its hemostatic properties and has been identified as a potential therapeutic agent in various medical applications.
Uses
Used in Hemostasis:
5C-aglycone is used as a hemostatic agent for its ability to regulate blood clotting and prevent excessive bleeding. Its role in maintaining the balance of coagulation and anticoagulation processes makes it a valuable component in the treatment of various bleeding disorders.
Used in Pain Management for Osteoporosis:
5C-aglycone is used as an adjunctive therapy for the pain associated with osteoporosis. Its potential to alleviate pain and improve the quality of life for patients suffering from this condition makes it a promising candidate for further research and development in the field of orthopedics.
Used in Pharmaceutical Research:
5C-aglycone's unique properties and metabolite status make it an interesting subject for pharmaceutical research. It may be explored for its potential applications in the development of new drugs targeting various health conditions, including those related to blood clotting and bone health.
Used in Nutritional Supplements:
Given its connection to Vitamin K2, 5C-aglycone may be utilized in the development of nutritional supplements aimed at supporting bone health and overall well-being. Its inclusion in these products could provide consumers with additional benefits related to hemostasis and pain management.
Check Digit Verification of cas no
The CAS Registry Mumber 34927-45-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,4,9,2 and 7 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 34927-45:
(7*3)+(6*4)+(5*9)+(4*2)+(3*7)+(2*4)+(1*5)=132
132 % 10 = 2
So 34927-45-2 is a valid CAS Registry Number.
InChI:InChI=1/C16H16O4/c1-9(16(19)20)7-8-11-10(2)14(17)12-5-3-4-6-13(12)15(11)18/h3-6,9H,7-8H2,1-2H3,(H,19,20)
34927-45-2Relevant articles and documents
Convenient, scalable synthesis of 2-methyl-3-(3′,3′-carboxymethylpropyl)-1,4-naphthoquinone, the principal vitamin K urinary metabolite
Goebel, Erik S.,Barany, George
, p. 5850 - 5851 (2016)
The ultimate metabolite of vitamin K, 2-methyl-3-(3′,3′-carboxymethylpropyl)-1,4-naphthoquinone (1), has been shown to be biologically active and may be used as a measure of vitamin K levels in the body. We report a facile, five-step synthesis of 1 that requires only two isolated intermediates and a single chromatographic purification, and provides the title product in 26% overall yield. The structure of one of the intermediates was confirmed by X-ray crystallography.
Efficient Syntheses of Vitamin K Chain-Shortened Acid Metabolites
Teitelbaum, Aaron M.,Scian, Michele,Nelson, Wendel L.,Rettie, Allan E.
, p. 944 - 948 (2015/03/30)
Vitamin K sequentially undergoes ω-oxidation followed by successive rounds of β-oxidation to ultimately produce two chain-shortened carboxylic acid metabolites, vitamin K acid 1 and vitamin K acid 2. Two facile syntheses of these acid metabolites are desc
