34959-72-3Relevant articles and documents
CONVERSION OF PENICILLIN G INTO CEPHALEXIN EMPLOYING A SECOND-ORDER ASYMMETRIC TRANSFORMATION
Cooper, John,Humber, David C.,Long, Alan G.
, p. 1469 - 1478 (2007/10/02)
2'S- and 2'R- and S- cephalexin, (5b) and (5c) respectively, both available in six stages from penicillin G, have each been converted to the more useful 2'R-isomer (5a) by a base catalysed epimerization and selective crystallization process involving the N-nitrosoimidazolidinyl derivatives (7).