3496-88-6Relevant articles and documents
Synthesis of 6-azacholesten-3-ones: Potent inhibitors of 5α-reductase
Haffner, Curt
, p. 4039 - 4042 (1995)
4-Cholesten-3-one was converted into 6-azacholesten-3-ones (7, 14 and 15). These compounds proved to be potent inhibitors of both type 1 and 2 human 5α-reductase.
Synthesis of deuterium and tritium labelled 7-hydroxy- and 7-oxosterols
Schabdach,Schroeder,Seifert
, p. 329 - 336 (1998)
Deuterium and tritium 3,7-bis-labelled 7-hydroxysterols 3 - 5 were prepared by reduction of the 3,7-dioxosterols 1, 2 with NaB2H4 and NaB3H4. Regioselective oxidation of the deuterium 3,7-bislabelled 7- hydroxysterols 3, 4 with CrO3/DMP led to the 3-labelled 7-oxosterols 6, 7. The 3,7-dioxosterols 1, 2 were synthesized starting from cholesterol and β- sitosterol.