350479-90-2

Basic information

• Product Name: (S,E)-N-benzylidene-4-methylbenzenesulfinamide
• Synonyms: (S,E)-N-benzylidene-4-methylbenzenesulfinamide
• CAS NO: 350479-90-2
• Molecular Weight: 243.329
• Mol File: 350479-90-2.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: (S,E)-N-benzylidene-4-methylbenzenesulfinamide(CAS DataBase Reference)
• NIST Chemistry Reference: (S,E)-N-benzylidene-4-methylbenzenesulfinamide(350479-90-2)
• EPA Substance Registry System: (S,E)-N-benzylidene-4-methylbenzenesulfinamide(350479-90-2)

Safety Data

• Hazardous Substances Data: 350479-90-2(Hazardous Substances Data)

Upstream product

• 1517-82-4 (1R,2S,5R,SS)-(-)-menthyl p-toluenesulfinate 
• 100-52-7 benzaldehyde 
• 1517-82-4 (-)-menthyl p-toluenesulfinate 
• 749253-91-6 (S_S,2S,3S)-(+)-ethyl 2-N-(diphenylmethylideneamino)-3-N-(p-toluenesulfinyl)amino-3-phenylpropanoate 
• 930299-14-2 ethyl (S_S,2R,3S)-(+)-2-N-(diphenylmethyleneamino)-3-N-(p-toluenesulfinyl)amino-3-phenylpropanoate 
• 50444-99-0 (1R,2S,5R)-menthyl-(S)-p-toluenesulfinate 
• 188447-91-8 (S)-p-toluenesulfinimide 
• 100-47-0 benzonitrile 
• 190448-84-1 (1S,5R,7R)-10,10-Dimethyl-4-((R)-toluene-4-sulfinyl)-3-thia-4-aza-tricyclo[5.2.1.0^1,5]decane 3,3-dioxide 
• 4039-32-1 lithium hexamethyldisilazane 
• 82495-70-3 (2S)-2-p-toluenesulfonamido-3-phenylpropanol 
• 1279697-25-4 (2R,4S)-4-Benzyl-5,5-dimethyl-3-tosyl-1,2,3-oxathiazolidine 2-oxide 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 1279696-96-6 (2R,4S)-3-[(4-methylphenyl)sulfonyl]-4-(phenylmethyl)-1,2,3-oxathiazolidine 2-oxide 

Downstream Products

• 181874-01-1 trans-(S_S,2R,3S)-(+)-N-(p-toluenesulfinyl)-2-methyl-2-carbomethoxy-3-phenylaziridine 
• 213909-35-4 4-Methyl-benzenesulfinic acid ((Z)-(1R,2S)-2-benzenesulfonyl-5-hydroxy-1-phenyl-pent-3-enyl)-amide 
• 220586-50-5 diethyl (S_s,1S,2R)-1-chloro-2-phenyl-2-(p-toluenesulfinamido)ethylphosphonate 
• 220586-51-6 diethyl (S_s,1R,2R)-1-chloro-2-phenyl-2-(p-toluenesulfinamido)ethylphosphonate 
• 220841-41-8 (Z)-3-Phenyl-2-[(S)-phenyl-((S)-toluene-4-sulfinylamino)-methyl]-but-2-enoic acid ethyl ester 
• 220841-40-7 3,3-Diphenyl-2-[(S)-phenyl-((S)-toluene-4-sulfinylamino)-methyl]-acrylic acid ethyl ester 

Relevant articles and documents

Multicomponent synthesis of chiral sulfinimines

Two oxathiozolidine-S-oxide templates have been developed and used in a four-component coupling protocol for the synthesis of a wide range of chiral sulfinimines in high enantiomeric excesses. The templates can be synthesized from cheap commodity chemicals in three steps in high yields. Furthermore the template is easily recovered in high yields for recycling.

Asymmetric synthesis of anti- and syn-2,3-diamino esters using sulfinimines. Water and concentration effects

(Chemical Equation Presented) In the absence of water, an excess of the lithium enolate of N-(diphenylmethylene)glycine ethyl ester (4) adds to sulfinimines to give syn-2,3-diamino esters 6, and in the presence of water, this enolate gives the anti-2,3-diamino esters 5. These unusual results are interpreted in terms of those factors that inhibit the retro-Mannich fragmentation in the diamino esters.

Stereoselective synthesis of β-substituted β-amino sulfones and sulfonamides via addition of sulfonyl anions to chiral N-sulfinyl imines

A highly stereoselective synthesis of β-amino sulfones and sulfonamides via addition of sulfonyl anions to chiral N-sulfinyl imines is described. The addition reaction proceeds in good yield (75-99%) and stereoselectivity.