350846-54-7

Basic information

• Product Name: (E,E)-2-pyridyldimethyl(4-phenylbuta-1,3-dienyl)silane
• Synonyms: (E,E)-2-pyridyldimethyl(4-phenylbuta-1,3-dienyl)silane
• CAS NO: 350846-54-7
• Molecular Weight: 265.43
• Mol File: 350846-54-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E,E)-2-pyridyldimethyl(4-phenylbuta-1,3-dienyl)silane(CAS DataBase Reference)
• NIST Chemistry Reference: (E,E)-2-pyridyldimethyl(4-phenylbuta-1,3-dienyl)silane(350846-54-7)
• EPA Substance Registry System: (E,E)-2-pyridyldimethyl(4-phenylbuta-1,3-dienyl)silane(350846-54-7)

Safety Data

• Hazardous Substances Data: 350846-54-7(Hazardous Substances Data)

Upstream product

• 21032-48-4 2-(dimethylhydrosilyl)pyridine 
• 104-55-2 3-phenyl-propenal 
• 243468-48-6 bis(2-pyridyldimethylsilyl)methane 

Downstream Products

• 52010-91-0 4-((1E,3E)-4-phenylbuta-1,3-dienyl)benzaldehyde 
• 1465-80-1 ethyl (E,E)-4-<4-phenylbuta-1,3-dien-1-yl>benzoate 

Relevant articles and documents

Facile generation of [bis(2-pyridyldimethylsilyl)methyl]lithium and its reaction with carbonyl compounds. New method for the stereoselective synthesis of vinylsilanes

The generation of (2-PyMe2Si)2CHLi was easily accomplished by the deprotonation of (2-PyMe2Si)2CH2 using n-BuLi in Et2O. The 1H NMR analysis of (2-PyMe2Si)2CHLi in Et2O-d10 revealed the coordination of both pyridyl groups to lithium. Thus generated (2-PyMe2Si)2CHLi was found to react with a variety of aldehydes and ketones to give the corresponding vinylsilanes in extremely high yields with complete stereoselectivities (>99% E).