21032-48-4 Usage
Description
2-(DIMETHYLSILYL)PYRIDINE, also known as 2-Pyridyldimethylsilane, is an organic compound with the molecular formula C7H11NSi. It is characterized by the presence of a pyridyl group attached to a dimethylsilyl moiety. 2-(DIMETHYLSILYL)PYRIDINE is known for its reactivity and utility in various chemical reactions, particularly in the field of organic synthesis.
Uses
Used in Chemical Synthesis:
2-(DIMETHYLSILYL)PYRIDINE is used as a reagent for metal-catalyzed hydrosilylation of alkynes and alkenes. Its unique structure, featuring a catalyst-directing pyridyl group on silicon, allows it to exhibit greater reactivity in Rh-catalyzed hydrosilylation of alkenes compared to other related hydrosilanes. The basic pyridyl group also facilitates easy product separation and catalyst recovery through simple acid/base extraction.
Used in Organic Reactions:
2-(DIMETHYLSILYL)PYRIDINE serves as a useful scaffold for a number of reactions, including hydrosilylation, cross-coupling, and olefination. Its versatile nature makes it a valuable compound in the development of new synthetic routes and the synthesis of complex organic molecules.
Physical Properties:
2-(DIMETHYLSILYL)PYRIDINE has a boiling point of 68-72 °C at a pressure of 20 mm Hg, which indicates its relatively low volatility and suitability for use in various chemical processes.
Preparation
2-Pyridyldimethylsilane can be prepared by reaction of 2-pyridyllithium
with chlorodimethylsilane in dry Et2O at ?78°Cunder
argon.
Check Digit Verification of cas no
The CAS Registry Mumber 21032-48-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,0,3 and 2 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 21032-48:
(7*2)+(6*1)+(5*0)+(4*3)+(3*2)+(2*4)+(1*8)=54
54 % 10 = 4
So 21032-48-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H11NSi/c1-9(2)7-5-3-4-6-8-7/h3-6,9H,1-2H3
21032-48-4Relevant articles and documents
Synthesis and coordinating properties of 2-pirydildimethylsilane
Ang, H. G.,Kwik, W. L.
, p. 27 - 30 (1989)
The reaction of 2-pyridyldimethylsilane with rhenium carbonyl yields 2-C5H4NSi(CH3)2Re(CO)4 in which the ligand is bonded through N and Si donor atoms.The ligand also reacts with Ir(CO)Cl(PPh3)3 to give 2-C5H4NSi(CH3)2Ir(CO)Cl(PPh3)2H.
Oxidation of 2-Pyridyldimethylsilyl Group to Hydroxyl Group by H2O2/KF. Implication of Fluoride Ion Accelerated 2-Pyridyl-Silyl Bond Cleavage
Itami, Kenichiro,Mitsudo, Koichi,Yoshida, Jun-Ichi
, p. 8709 - 8714 (2007/10/03)
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