35088-86-9

Basic information

• Product Name: 4-methoxyl-N-propylbenzenesulfonamide
• Synonyms: 4-methoxyl-N-propylbenzenesulfonamide
• CAS NO: 35088-86-9
• Molecular Weight: 229.3
• Mol File: 35088-86-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 4-methoxyl-N-propylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methoxyl-N-propylbenzenesulfonamide(35088-86-9)
• EPA Substance Registry System: 4-methoxyl-N-propylbenzenesulfonamide(35088-86-9)

Safety Data

• Hazardous Substances Data: 35088-86-9(Hazardous Substances Data)

Upstream product

• 107-10-8 propylamine 
• 156098-16-7 triisopropyl-(4-methoxyphenylsulfanyl)-silane 
• 154853-46-0 2,4-dinitrophenyl 4-methoxybenzenesulfonate 
• 98-68-0 4-methoxy-phenyl-sulphonyl chloride 
• 6140-09-6 sodium 4-methoxy-benzenesulfonate 
• 34954-40-0 N-allyl-4-methoxybenzenesulfonamide 

Downstream Products

• 1392414-67-3 (Z)-N-(1-bromo-1-octen-2-yl)-N-propyl-p-methoxybenzenesulfonamide 

Relevant articles and documents

Cobalt-catalyzed alkene hydrogenation by reductive turnover

Earth abundant metal catalysts hold advantages in cost, environmental burden and chemoselectivity over precious metal catalysts. Differences in reactivity for a given metal center result from ligand field strength, which can promote reaction through either open- or closed-shell carbon intermediates. Herein we report a simple protocol for cobalt-catalyzed alkene reduction. Instead of using an oxidative turnover mechanism that requires stoichiometric hydride, we find a reductive turnover mechanism that requires stoichiometric proton. The reaction mechanism appears to involve coordination and hydrocobaltation of terminal alkenes.

Intermolecular Anti-Markovnikov Hydroamination of Unactivated Alkenes with Sulfonamides Enabled by Proton-Coupled Electron Transfer

Here we report a catalytic method for the intermolecular anti-Markovnikov hydroamination of unactivated alkenes using primary and secondary sulfonamides. These reactions occur at room temperature under visible light irradiation and are jointly catalyzed by an iridium(III) photocatalyst, a dialkyl phosphate base, and a thiol hydrogen atom donor. Reaction outcomes are consistent with the intermediacy of an N-centered sulfonamidyl radical generated via proton-coupled electron transfer activation of the sulfonamide N-H bond. Studies outlining the synthetic scope (>60 examples) and mechanistic features of the reaction are presented.

Oxidation of aromatic and aliphatic triisopropylsilanylsulfanyls to sulfonyl chlorides: Preparation of sulfonamides

A series of aromatic and aliphatic triisopropylsilanylsulfanyls were prepared and oxidized to the sulfonyl chlorides with KNO3/SO 2Cl2. The sulfonyl chlorides were characterized via their conversion to sulfonamides.