35107-12-1

Basic information

• Product Name: Hexanoic acid, 3,6-bis[[(phenylmethoxy)carbonyl]amino]-, (3S)-
• CAS NO: 35107-12-1
• Molecular Formula: C22H26N2O6
• Molecular Weight: 414.458
• Mol File: 35107-12-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Hexanoic acid, 3,6-bis[[(phenylmethoxy)carbonyl]amino]-, (3S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Hexanoic acid, 3,6-bis[[(phenylmethoxy)carbonyl]amino]-, (3S)-(35107-12-1)
• EPA Substance Registry System: Hexanoic acid, 3,6-bis[[(phenylmethoxy)carbonyl]amino]-, (3S)-(35107-12-1)

Safety Data

• Hazardous Substances Data: 35107-12-1(Hazardous Substances Data)

Upstream product

• 501-53-1 benzyl chloroformate 
• 504-21-2 (3S)-β-lysine 
• 2274-58-0 (S)-2,5-bis-(benzyloxycarbonylamino)pentanoic acid 
• 69677-00-5 N^α.N^δ-bis-benzyloxycarbonyl-L-ornithyl chloride 
• 57133-27-4 (S)-N,N-dibenzyloxycarbonyl-β-lysine methyl ester 
• 37682-54-5 (S)-3,6-Bis-benzyloxycarbonylamino-hexanoic acid benzyl ester 

Downstream Products

• 37682-58-9 (S)-6-Benzyloxycarbonylamino-3-((S)-3,6-bis-benzyloxycarbonylamino-hexanoylamino)-hexanoic acid methyl ester 
• 83663-06-3 {5-[(2S,4S,5R,6R)-2-Allyloxy-4-hydroxy-6-hydroxymethyl-5-(2-methoxy-ethoxymethoxy)-tetrahydro-pyran-3-ylcarbamoyl]-4-benzyloxycarbonylamino-pentyl}-carbamic acid benzyl ester 
• 504-21-2 (3S)-β-lysine 
• 37682-54-5 (S)-3,6-Bis-benzyloxycarbonylamino-hexanoic acid benzyl ester 
• 58773-34-5 5-deoxy-3-epi-negamycine 

Relevant articles and documents

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Asymmetric Syntheses of the Naturally Ocurring β-Amino Acids, β-Lysine, β-Leucine and β-Phenyl-β-alanine via Nitrone Cycloaddition

A general asymmetric synthesis of β-amino acids is based on the dipolar cycloaddition of nitrones 7 (R* chiral) with vinyl acetate 8a, ketene acetals 8b or α-chloroacrylonitrile 8c.The cycloadducts 9 are converted either directly (9b) or via the isoxazolidones 10 (9a, 9c) into the free β-amino acids 11.Diastereoselectivity at C-3 in the adducts 9 ranges between 2:1 and 11:1.The natural β-amino acids, β-lysine, β-leucine and β-phenyl-β-alanine, have been prepared in this way.