504-21-2

Basic information

• Product Name: (3S)-3,6-Diaminohexanoic acid
• Synonyms: (3S)-3-(3-Aminopropyl)-β-alanine;(3S)-3,6-Diaminohexanoic acid;(S)-3-(3-Aminopropyl)-β-alanine;(S)-3,6-Diaminohexanoic acid
• CAS NO: 504-21-2
• Molecular Formula: C₆H₁₄N₂O₂
• Molecular Weight: 146.1876
• Mol File: 504-21-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 319.6°Cat760mmHg
• Flash Point: 147.1°C
• Appearance: /
• Density: 1.125g/cm³
• Vapor Pressure: 6.99E-05mmHg at 25°C
• Refractive Index: 1.503
• CAS DataBase Reference: (3S)-3,6-Diaminohexanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (3S)-3,6-Diaminohexanoic acid(504-21-2)
• EPA Substance Registry System: (3S)-3,6-Diaminohexanoic acid(504-21-2)

Safety Data

• Hazardous Substances Data: 504-21-2(Hazardous Substances Data)

Usage

General Description

(3S)-3,6-Diaminohexanoic acid, also known as D-lysine, is a compound that belongs to the group of amino acids. It is an important building block for proteins and is commonly found in various food sources such as meat, fish, eggs, and dairy products. D-lysine plays a crucial role in many biological processes, including the formation of collagen, the maintenance of healthy skin and bones, and the synthesis of carnitine, a substance that helps the body turn fat into energy. Additionally, D-lysine has been studied for its potential therapeutic applications in the treatment of various health conditions, including herpes simplex virus infections and anxiety. Overall, (3S)-3,6-Diaminohexanoic acid is an essential amino acid that is vital for maintaining overall health and well-being.

InChI:InChI=1/C6H14N2O2/c7-3-1-2-5(8)4-6(9)10/h5H,1-4,7-8H2,(H,9,10)

Upstream product

• 86088-69-9 β-lysine di-N-phthaloyl methyl ester 
• 58773-34-5 5-deoxy-3-epi-negamycine 
• 56-87-1 L-lysine 
• 35107-12-1 (S)-N,N'-Dibenzyloxycarbonyl-β-lysine 
• 118743-79-6 (3S)-(4-Benzyloxycarbonylaminobutyl)-N-<(R)-(-)-α-methylbenzyl>isoxazolidin-5-one 
• 186581-53-3 diazomethane 
• 118743-76-3 3(S)-(4-Benzyloxycarbonylaminobutyl)-N-<(R)-(-)-α-methylbenzyl>isoxazolidin-5-ol 
• 118743-83-2 5-Acetoxy-3(S)-(4-benzyloxycarbonylaminobutyl)-N-<(R)-(-)-α-methylbenzyl>isoxazolidine 
• 70548-25-3 di-N-phthalimide l-ornithine 

Downstream Products

• 35761-12-7 (S)-3,6-bis-benzoylamino-hexanoic acid 
• 37682-54-5 (S)-3,6-Bis-benzyloxycarbonylamino-hexanoic acid benzyl ester 
• 35107-12-1 (S)-N,N'-Dibenzyloxycarbonyl-β-lysine 
• 37682-58-9 (S)-6-Benzyloxycarbonylamino-3-((S)-3,6-bis-benzyloxycarbonylamino-hexanoylamino)-hexanoic acid methyl ester 

Relevant articles and documents

Biochemical Characterization of an Arginine 2,3-Aminomutase with Dual Substrate Specificity

The radical S-adenosylmethionine (SAM) aminomutases represent an important pathway for the biosynthesis of β-amino acids. In this study, we report biochemical characterization of BlsG involved in blasticidin S biosynthesis as a radical SAM arginine 2,3-aminomutase. We showed that BlsG acts on both L-arginine and L-lysine with comparable catalytic efficiencies. Similar dual substrate specificity was also observed for the lysine 2,3-aminomutase from Escherichia coli (LAMEC). The catalytic efficiency of LAMEC is similar to that of BlsG, but is significantly lower than that of the enzyme from Clostridium subterminale (LAMCS), which acts only on L-lysine rather than on L-arginine. Moreover, we showed that enzymes can be grouped into two major phylogenetic clades, each corresponding to a certain C3 stereochemistry of the β-amino acid product. Our study expands the radical SAM aminomutase members and provides insights into enzyme evolution, supporting a trade-off between substrate promiscuity and catalytic efficiency.

Microbial products. III. Epi-deoxynegamycin from a micromonospora

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Enantioselective Synthesis of Optically Pure (R)- and (S)-β-Lysine via Nitrone Cycloaddition

Optically pure (R)- and (S)-β-lysines have been obtained via cycloaddition of chiral nitrone (4) to vinyl acetate, followed by facile chromatographic separation of the four resulting acetates (5) into two pairs of C-5 epimers and conversion of each pair i