352304-04-2

Basic information

• Product Name: {2-[3-(2,6-difluoro-benzyl)-5-(1-ethoxy-vinyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenyl-ethyl}-carbamic acid tert-butyl ester
• CAS NO: 352304-04-2
• Molecular Weight: 541.595
• Mol File: 352304-04-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {2-[3-(2,6-difluoro-benzyl)-5-(1-ethoxy-vinyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenyl-ethyl}-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {2-[3-(2,6-difluoro-benzyl)-5-(1-ethoxy-vinyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenyl-ethyl}-carbamic acid tert-butyl ester(352304-04-2)
• EPA Substance Registry System: {2-[3-(2,6-difluoro-benzyl)-5-(1-ethoxy-vinyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenyl-ethyl}-carbamic acid tert-butyl ester(352304-04-2)

Safety Data

• Hazardous Substances Data: 352304-04-2(Hazardous Substances Data)

Upstream product

• 69385-30-4 2,6-difluorobenzylamine 
• 17751-24-5 N-(2,6-difluorobenzyl) urea 
• 618914-13-9 1-(2,6-difluorobenzyl)-3-(3-oxobutyryl)urea 
• 352303-66-3 5-bromo-1-(2,6-difluoro-benzyl)-6-methyl-1H-pyrimidine-2,4-dione 
• 97674-02-7 tributyl(1-ethoxyvinyl)stannane 
• 352303-69-6 {(R)-2-[5-bromo-3-(2,6-difluoro-benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenyl-ethyl}-carbamic acid tert-butyl ester 
• 352303-65-2 N-1-(2,6-difluorobenzyl)-6-methyluracil 

Relevant articles and documents

Synthesis and structure-activity relationships of uracil derived human GnRH receptor antagonists: (R)-3-[2-(2-amino)phenethyl]-1-(2,6-difluorobenzyl)-6- methyluracils containing a substituted thiophene or thiazole at C-5

The design and synthesis of a number of 5-thiazolyl and 5-thienyl substituted uracils is described and results from SAR studies are summarized. The best compound showed Ki = 2 nM. The synthesis of a series of (R)-3-[2-(2-amino)phenethyl]-1-(2,6