35387-19-0Relevant articles and documents
Acid-promoted fries rearrangements of benzannulated lactones
Cambie, Richard C.,Mitchell, Lorna H.,Rutledge, Peter S.
, p. 1167 - 1174 (2007/10/03)
The scope of acid-promoted Fries rearrangements of benzannulated lactones has been examined. The reaction is applicable to seven-membered lactones possessing a sufficiently activated aromatic ring but not to six-membered lactones, and it proceeds in higher yield for diterpenoid lactones than for lower molecular weight lactones. The structures of the 2,6-methano-bridged benzoxocin side products (23), (24), and (25) from rearrangement of the diterpenoid lactone (11) have been assigned.