35387-95-2 Usage
Description
Methyl 2-iodo-3-methoxybenzoate is a chemical compound that belongs to the class of esters. It is characterized by the presence of a methyl group, an iodine atom, and a methoxy group attached to a benzene ring. This unique chemical structure and reactivity make it a valuable compound for various applications in organic synthesis and pharmaceutical research.
Uses
Used in Organic Synthesis:
Methyl 2-iodo-3-methoxybenzoate is used as a synthetic intermediate for the preparation of various organic compounds. Its reactivity and functional groups allow for a wide range of chemical reactions, making it a versatile building block in the synthesis of complex organic molecules.
Used in Pharmaceutical Research:
Methyl 2-iodo-3-methoxybenzoate is used as a starting material or intermediate in the development of new pharmaceutical agents. Its unique structure can be exploited to design and synthesize novel drug candidates with potential therapeutic applications.
Used in Chemical Research:
Methyl 2-iodo-3-methoxybenzoate is used as a research tool in the study of chemical reactions and mechanisms. Its reactivity and functional groups provide insights into the behavior of similar compounds and contribute to the understanding of organic chemistry.
It is important to handle methyl 2-iodo-3-methoxybenzoate with care, as it may pose health and environmental hazards if not properly managed. Additionally, its potential uses and applications should be carefully considered within the context of safety and regulatory guidelines.
Check Digit Verification of cas no
The CAS Registry Mumber 35387-95-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,3,8 and 7 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 35387-95:
(7*3)+(6*5)+(5*3)+(4*8)+(3*7)+(2*9)+(1*5)=142
142 % 10 = 2
So 35387-95-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H9IO3/c1-12-7-5-3-4-6(8(7)10)9(11)13-2/h3-5H,1-2H3
35387-95-2Relevant articles and documents
Optimization of a Benzoylpiperidine Class Identifies a Highly Potent and Selective Reversible Monoacylglycerol Lipase (MAGL) Inhibitor
Granchi, Carlotta,Lapillo, Margherita,Glasmacher, Sandra,Bononi, Giulia,Licari, Cristina,Poli, Giulio,El Boustani, Maguie,Caligiuri, Isabella,Rizzolio, Flavio,Gertsch, Jürg,Macchia, Marco,Minutolo, Filippo,Tuccinardi, Tiziano,Chicca, Andrea
, p. 1932 - 1958 (2019/02/26)
Monoacylglycerol lipase (MAGL) is the enzyme degrading the endocannabinoid 2-arachidonoylglycerol, and it is involved in several physiological and pathological processes. The therapeutic potential of MAGL is linked to several diseases, including cancer. The development of MAGL inhibitors has been greatly limited by the side effects associated with the prolonged MAGL inactivation. Importantly, it could be preferable to use reversible MAGL inhibitors in vivo, but nowadays only few reversible compounds have been developed. In the present study, structural optimization of a previously developed class of MAGL inhibitors led to the identification of compound 23, which proved to be a very potent reversible MAGL inhibitor (IC50 = 80 nM), selective for MAGL over the other main components of the endocannabinoid system, endowed of a promising antiproliferative activity in a series of cancer cell lines and able to block MAGL both in cell-based as well as in vivo assays.
Light-driven rotary molecular motors on gold nanoparticles
Pollard, Michael M.,Ter Wiel, Matthijs K. J.,Van Delden, Richard A.,Vicario, Javier,Koumura, Nagatoshi,Van Den Brom, Coenraad R.,Meetsma, Auke,Feringa, Ben L.
supporting information; experimental part, p. 11610 - 11622 (2009/12/09)
We report the synthesis of unidirectional light-driven rotary molecular motors based on chiral overcrowded alkenes and their immobilisation on the surface of gold nanoparticles through two anchors. Using a combination of 1H and 13C N
