3539-40-0

Basic information

• Product Name: ethyl 2-(tetrahydro-2H-pyran-2-yloxy)propanoate
• Synonyms: Ethyl 2-(tetrahydro-2H-pyran-2-yloxy)propanoate; Propanoic acid, 2-[(tetrahydro-2H-pyran-2-yl)oxy]-, ethyl ester
• CAS NO: 3539-40-0
• Molecular Formula: C₁₀H₁₈O₄
• Molecular Weight: 202.2475
• Mol File: 3539-40-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 292.7°C at 760 mmHg
• Flash Point: 125.6°C
• Density: 1.05g/cm³
• Vapor Pressure: 0.00181mmHg at 25°C
• Refractive Index: 1.448
• CAS DataBase Reference: ethyl 2-(tetrahydro-2H-pyran-2-yloxy)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(tetrahydro-2H-pyran-2-yloxy)propanoate(3539-40-0)
• EPA Substance Registry System: ethyl 2-(tetrahydro-2H-pyran-2-yloxy)propanoate(3539-40-0)

Safety Data

• Hazardous Substances Data: 3539-40-0(Hazardous Substances Data)

Usage

General Description

Ethyl 2-(tetrahydro-2H-pyran-2-yloxy)propanoate is a chemical compound with the molecular formula C9H16O3. It is commonly used as a flavoring agent in the food industry, adding a fruity and sweet aroma to various products. ethyl 2-(tetrahydro-2H-pyran-2-yloxy)propanoate is also used in the production of perfumes and fragrances due to its pleasant odor. Furthermore, it has been found to have potential pharmaceutical applications, such as in the formulation of drugs and medicines. Ethyl 2-(tetrahydro-2H-pyran-2-yloxy)propanoate is considered safe for use in food and cosmetic products when used in accordance with regulations and guidelines set by regulatory bodies.

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 97-64-3 ethyl 2-hydroxypropionate 
• 76-26-6 camphor-10-sulfonic acid 
• 687-47-8 (S)-Ethyl lactate 

Downstream Products

• 3539-39-7 (S)-(+)-2-Tetrahydropyran-2-yloxypropan-1-ol 
• 76946-21-9 (2S)-2-(tetrahydro-2H-pyran-2-yloxy)propan-1-ol 
• 3539-39-7 (S)-(-)-2-(tetrahydropyranyloxy)propanol 
• 42274-61-3 (S)-(-)-2-(tetrahydropyranyloxy)propyl p-toluenesulfonate 
• 143331-41-3 (2S,12S)-(-)-2,12-bis(tetrahydropyranyloxy)-7-trityl-7-aza-4,10-dioxatridecane 
• 131889-37-7 Methyl 4-<(S)-2-(tetrahydro-2-pyranoxy)propoxy>-benzoate 
• 42274-61-3 (2S)-2-(tetrahydro-2H-pyran-2-yloxy)propyl 4-methylbenzenesulfonate 

Relevant articles and documents

BIARYL DERIVATIVES AS YAP/TAZ-TEAD PROTEIN-PROTEIN INTERACTION INHIBITORS

The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; (I) a method for manufacturing said compound, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition comprising said compound.

New Symmetrical Chiral Dibenzyl- and Diphenyl-Substituted Diamido-, Dithionoamido-, Diaza-, and Azapyridino-18-crown-6 Ligands

Eleven new chiral macrocycles (1-11, see Figure 1) of the pyridino-18-crown-6 type have been prepared.Nine diazapyridino-crown ligands contain two amide (1, R = benzyl; 4, R = phenyl), two N-methylamide (7, R = phenyl), two thionoamide (2, R = benzyl; 5,

An (S)-(+)-Lactic Acid Route to (2S,6R,8S)-2,8-Dimethyl-1,7-dioxaspiroundecane and (2S,6R,8S)-2-Ethyl-8-methyl-1,7-dioxaspiroundecane and Demonstration of their Presence in the Rectal Glandular Secretion of Bactrocera nigrotibialis (Perkin)

The chiral iodide resulting from reduction and iodination of the tetrahydropyran-2-yl ether of ethyl (S)-(+)-lactate has been engaged in a free-radical addition to acrylonitrile.The resulting protected hydroxy nitrile, on reaction with pent-4-enylmagnesium bromide afforded (S)-2-tetrahydropyran-2-yloxyundec-10-en-6-one.Oxymercuration of this hydroxy enone, under reversible conditions, employing aqueous acid-tetrahydrofuran, effected simultaneous deprotection and cyclisation, and in situ biphasic demercuration with sodium borohydride provided essentially stereochemically pure (2S,6R,8S)-2,8-dimethyl-1,7-dioxaspiroundecane .Epoxidation of the protected hydroxy enone, followed by dimethylcuprate ring-opening and cyclisation, provided a mixture of the (E,E) and the two possible (E,Z)-diastereomers of 2-ethyl-8-methyl-1,7-dioxaspiroundecane with the former being the (2S,6R,8S) stereoisomer.Separation of the (E,E) from the two (E,Z) isomers was achieved by preparative gas chromatography.GC analysis of these samples and of the rectal glandular secretion of male Bactrocera nigrobialis, using a cyclodextrin-based phase, demonstrated that (2S,6R,8S)-stereoisomers of the 2,8-dimethyl-and 2-ethyl-8-methyl-1,7-dioxaspiroundecanes were the natural products, with no detectable level of the antipodes.