35472-56-1

Basic information

• Product Name: Benzoic acid, 2-(methylamino)-, ethyl ester
• Synonyms: Benzoic acid, 2-(methylamino)-, ethyl ester;ETHYLN-METHYLANTHRANILATE;2-(Methylamino)benzoic acid ethyl ester;o-(Methylamino)benzoic acid ethyl ester;Ethyl 2-(methylamino);ethyl methyl anthranilate
• CAS NO: 35472-56-1
• Molecular Formula: C₁₀H₁₃NO₂
• Molecular Weight: 179.22
• Mol File: 35472-56-1.mol
• Article Data: 18

Chemical Properties

• Melting Point: 39°C
• Boiling Point: 311.75°C (rough estimate)
• Flash Point: 58°C
• Appearance: /
• Density: 1.1248 (rough estimate)
• Vapor Pressure: 0.00887mmHg at 25°C
• Refractive Index: 1.5710 (estimate)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 2.77±0.10(Predicted)
• CAS DataBase Reference: Benzoic acid, 2-(methylamino)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-(methylamino)-, ethyl ester(35472-56-1)
• EPA Substance Registry System: Benzoic acid, 2-(methylamino)-, ethyl ester(35472-56-1)

Safety Data

• Hazardous Substances Data: 35472-56-1(Hazardous Substances Data)

Usage

Chemical Properties

Yellowish solid; fruity mandarin-type aroma.

Aroma threshold values

Medium strength odor, fruity type.

InChI:InChI=1/C10H13NO2/c1-3-13-10(12)8-6-4-5-7-9(8)11-2/h4-7,11H,3H2,1-2H3

Upstream product

• 64-17-5 ethanol 
• 119-68-6 N-Methylanthranilic acid 
• 87-25-2 2-ethoxycarbonylaniline 
• 74-88-4 methyl iodide 
• 23310-36-3 1-methyl-2,1-benzisothiazoline-3(1H)-one 
• 33923-02-3 methyl N-methyl-N-carbethoxyanthranilate 
• 2621-79-6 ethyl N-methyl-N-phenylcarbamate 
• 616-38-6 carbonic acid dimethyl ester 
• 141814-27-9 2-(2-Methoxyethoxy)ethyl methyl carbonate 
• 4214-38-4 (diphenylmethylene)triphenylphosphorane 
• 10328-92-4 N-Methylisatoic anhydride 
• 79228-33-4 N-carbethoxy-N-methylanthranilic acid 
• 201230-82-2 carbon monoxide 
• 100-61-8 N-methylaniline 

Downstream Products

• 94237-92-0 3-(methyl-nitroso-amino)-benzoic acid ethyl ester 
• 99105-33-6 N-chloroacetyl-N-methyl-anthranilic acid ethyl ester 
• 719-54-0 10-methyl-9, 10-dihydro-9-acridinone 
• 13082-16-1 1,2,3-Trimethoxy-N-methylacridon 
• 70744-03-5 3-amino-4-hydroxy-1-methyl-1H-quinolin-2-one 
• 57513-54-9 ethyl 4-hydroxy-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate 
• 100717-76-8 3-butyl-4-hydroxy-1-methylquinolin-2(1H)-one 
• 61352-48-5 ethyl N-(N-benzyl-2-pyrrolidinylcarbonyl)-N-methylanthranilate 
• 1234479-74-3 ethyl 2-((2-chloro-5-nitropyrimidin-4-yl)(methyl)amino)benzoate 
• 66427-86-9 2-chloro-11-methyl-5,11-dihydro-6H-benzo[e]pyrimido-[5,4-b][1,4]diazepin-6-one 
• 1234479-75-4 2-chloro-5,11-dimethyl-5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one 
• 1234480-46-6 2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-11-methyl-5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one 
• 1234479-76-5 2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-5,11-dimethyl-5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one 
• 1345539-83-4 ethyl 2-(2,6-difluoro-N-methylbenzamido)benzoate 

Relevant articles and documents

Palladium/copper-catalyzed aerobic oxidative C-H carbonylation for the synthesis of o-aminobenzoates

The palladium/copper-catalyzed aerobic oxidative C-H carbonylation for the synthesis of o-aminobenzoates is described. Molecular oxygen is used as the terminal oxidant. This methodology proceeds with a wide range of N-substituted anilines and alcohols and gives straightforward access to valuable o-aminobenzoates.

A novel pathway for the thermolysis of N-nitrosoanthranilates using flash vacuum pyrolysis leading to 7-aminophthalides

Flash vacuum pyrolysis of methyl N-methyl-N-nitrosoanthranilate leads to elimination of nitric oxide and disproportionation of the formed N-radical to 7-(methylamino)phthalide and methyl N-methylanthranilate. This transformation was found to be a convenient, solvent-free method for the preparation of 7-(methylamino)phthalides. An alternative route through pyrolysis of N-benzyl-N-methyl anthranilates was also investigated. This journal is

Acetic Acid Accelerated Visible-Light Photoredox Catalyzed N-Demethylation of N,N-Dimethylaminophenyl Derivatives

N,N-Dimethylaminophenyl moiety is a common fragment in medicinal chemistry as several pharmaceuticals bearing this privileged motif are on the market and under clinical evaluation. Oxidative N-demethylation is generally regarded as the major metabolic pathway. However, pharmacokinetics, metabolites studies as well as the further structural modification are precluded by the impracticality of chemical synthesis. Here we report that acetic acid can significantly accelerate visible-light photoredox catalyzed N-demethylation of N,N-dimethylaminophenyl derivatives. This approach is easy for large scale reaction and even for potential industrial manufacture. (Figure presented.).