35499-74-2

Basic information

• Product Name: 3’,4’,5,7-tetra-O-methyl-4β-hydroxycatechin
• Synonyms: 3’,4’,5,7-tetra-O-methyl-4β-hydroxycatechin
• CAS NO: 35499-74-2
• Molecular Weight: 362.379
• Mol File: 35499-74-2.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 3’,4’,5,7-tetra-O-methyl-4β-hydroxycatechin(CAS DataBase Reference)
• NIST Chemistry Reference: 3’,4’,5,7-tetra-O-methyl-4β-hydroxycatechin(35499-74-2)
• EPA Substance Registry System: 3’,4’,5,7-tetra-O-methyl-4β-hydroxycatechin(35499-74-2)

Safety Data

• Hazardous Substances Data: 35499-74-2(Hazardous Substances Data)

Upstream product

• 51079-25-5 (2R,3S)-(+)-catechin 3',4',5,7-tetramethyl ether 
• 6563-36-6 (2R^*,3S^*,4R^*)-flavan-3,4-diol 
• 14613-67-3 (2R^*,3S^*,4R^*)-5,7,3',4'-tetramethoxyflavan-3,4-diol 
• 67-56-1 methanol 
• 154-23-4 catechin 
• 480-18-2 taxifolin 
• 186581-53-3 diazomethane 
• 93527-39-0 (+)-(2R,3S,4S)-3,4,5,7,3',4'-hexahydroxyflavan 
• 6563-36-6 (+)-3',4',5,7-tetra-O-methyl-2,3-trans-dihydroquercetin 
• 69256-15-1 (2R,3S,4R)-(+)-3,4,5,7,3',4'-hexahydroxyflavan 
• 13650-85-6 (+/-)-taxifolin 3-acetyl-5,7,3',4'-tetramethyl ether 

Downstream Products

• 14613-67-3 (2R^*,3S^*,4S^*)-5,7,3',4'-tetramethoxyflavan-3,4-diol 
• 69256-15-1 (2R,3S,4R)-(+)-3,4,5,7,3',4'-hexahydroxyflavan 
• 78284-46-5 (2R,3S,4R)-2,3-trans-3,4-trans-3',4',5,7-tetramethoxy-4-(2,4-dimethoxyphenyl)flavan-3-ol 
• 78284-53-4 (2R,3S,4S)-2,3-trans-3,4-cis-3',4',5,7-tetramethoxy-4-(2,4-dimethoxyphenyl)flavan-3-ol 

Relevant articles and documents

Biooxidation of (+)-catechin and (-)-epicatechin into 3,4-dihydroxyflavan derivatives by the endophytic fungus Diaporthe sp. isolated from a tea plant

The microbial transformation of (+)-catechin (1) and (-)-epicatechin (2) by endophytic fungi isolated from a tea plant was investigated. It was found that the endophytic filamentous fungus Diaporthe sp. transformed them (1, 2) into the 3,4-cis-dihydroxyflavan derivatives, (+)-(2R,3S,4S)-3,4,5,7,3′,4′- hexahydroxyflavan (3) and (-)-(2R,3R,4R)-3,4,5,7,3′,4′-hexahydroxy- flavan (7), respectively, whereas (-)-catechin (ent-1) and (+)-epicatechin (ent-2) with a 2S-phenyl group resisted the biooxidation.

Chemoselective C-4 aerobic oxidation of catechin derivatives catalyzed by the trametes villosa laccase/1-hydroxybenzotriazole system: Synthetic and mechanistic aspects

Catechin derivatives were oxidized in air in the presence of the Trametes villosa laccase/1-hydroxybenzotriazole (HBT) system in buffered water/1,4-dioxane as reactionmedium. The oxidation products, flavan- 3,4-diols and the corresponding C-4 ketones, are

REGIO- AND STEREOSELECTIVE OXYGENATION OF FLAVAN-3-OL-, 4-ARYLFLAVAN-3-OL-, AND BIFLAVANOID-DERIVATIVES WITH POTASSIUM PERSULPHATE

The phenolic methyl ethers of flavan-3-ols, 4-arylflavan-3-ols, and (-)-fisetinidol-(4,8)-(+)-catechin biflavanoids are susceptible to regio- and stereoselective hydroxylation at C-4 in moderate to high yields with potassium persulphate/cupric sulphate in aqueous acetonitrile.The resultant 4-functionalized analogues are of both synthetic and degradative significance in condensed tannin chemistry.