35921-27-8

Basic information

• Product Name: 1-benzyl-4-(2-chlorophenyl) pyrrolidine-2,3-dione
• Synonyms: 1-benzyl-4-(2-chlorophenyl) pyrrolidine-2,3-dione
• CAS NO: 35921-27-8
• Molecular Weight: 311.768
• Mol File: 35921-27-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-benzyl-4-(2-chlorophenyl) pyrrolidine-2,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-4-(2-chlorophenyl) pyrrolidine-2,3-dione(35921-27-8)
• EPA Substance Registry System: 1-benzyl-4-(2-chlorophenyl) pyrrolidine-2,3-dione(35921-27-8)

Safety Data

• Hazardous Substances Data: 35921-27-8(Hazardous Substances Data)

Upstream product

• 23583-21-3 ethyl-3-benzylamino propionate 
• 100-46-9 benzylamine 
• 5336-50-5 1-benzyl-4,5-dioxopyrrolidine-3-carboxylic acid ethyl ester 
• 89-98-5 2-chloro-benzaldehyde 

Relevant articles and documents

NHC-catalyzed asymmetric α-regioselective [4 + 2] annulation to construct α-alkylidene-δ-lactones

The unprecedented NHC-catalyzed [4 + 2] annulation of α-bromoenals with dioxopyrrolidines is described. This protocol features broad substrate scope and allows rapid assembly of α-alkylidene-δ-lactones in good to high yields with excellent enantioselectivities. Notably, this process includes α-regioselective activation of azolium dienolate intermediates, which has not yet been reported.

Reactions of Sulfonium Salts with 2,3-Dioxopyrrolidine Derivatives: A Concise Synthesis of Spirocyclopropane

An efficient base-promoted spirocyclopropanation of 2,3-dioxopyrrolidine derivatives with sulfonium salts is described. This reaction enables a novel concise access to polysubstituted spirocyclopropane derivatives in good yields and with a trans/cis ratio of up to amp;gt;20:1 under mild conditions. amp;copy; Georg Thieme Verlag Stuttgart.