361436-25-1 Usage
Chemical structure
An indole ring with a hydroxyl group at the 5-position and a 4-fluorophenylmethyl group at the 3-position.
Classification
Serotonin reuptake inhibitor (SSRI)
Function
Potent and selective inhibitor of serotonin reuptake, used to treat depression, panic disorder, and obsessive-compulsive disorder.
Mechanism of action
Increases levels of serotonin in the brain, improving mood and reducing anxiety.
Off-label uses
Treatment of bulimia nervosa, premenstrual dysphoric disorder, and other conditions.
Side effects
Nausea, insomnia, and sexual dysfunction.
Risks
Serotonin syndrome when taken with other medications that increase serotonin levels.
Check Digit Verification of cas no
The CAS Registry Mumber 361436-25-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,6,1,4,3 and 6 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 361436-25:
(8*3)+(7*6)+(6*1)+(5*4)+(4*3)+(3*6)+(2*2)+(1*5)=131
131 % 10 = 1
So 361436-25-1 is a valid CAS Registry Number.
361436-25-1Relevant articles and documents
Novel heterocyclic thyromimetics
Haning, Helmut,Woltering, Michael,Mueller, Ulrich,Schmidt, Gunter,Schmeck, Carsten,Voehringer, Verena,Kretschmer, Axel,Pernerstorfer, Josef
, p. 1835 - 1840 (2007/10/03)
Novel heterocycle-fused thyromimetics are presented carrying indoles or indazoles instead of the phenolic group in T3. Potent agonists were identified in both series. SAR trends are examined and found to be mostly consistent with previously published thyromimetics. Moderate THRβ selectivity (approx. 10-fold) was observed in the indole series using isoform-selective transient THR transfection assays
