361456-46-4Relevant articles and documents
ENZYME INHIBITORS
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Page/Page column 39; 33, (2019/06/17)
This invention relates to enzyme inhibitors that are inhibitors of plasma kallikrein and to pharmaceutical compositions containing and the uses of, such inhibitors.Specifically, the invention relates to compounds of formula (I): Formula (I) and tautomers,stereoisomers, pharmaceutically acceptable salts and solvates thereof; wherein R1 to R15, and Q are as defined herein.
THIAZOLE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR
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Page/Page column 57, (2009/09/05)
The present invention provides a novel thiazole derivative useful as a VAP-1 inhibitor, a pharmaceutical agent for the prophylaxis or treatment of VAP-1 associated diseases and the like. A compound represented by the formula (I): wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof.
PHARMACEUTICAL PREPARATIONS COMPRISING INSULIN, ZINC IONS AND A ZINC-BINDING LIGAND
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Page/Page column 319-320, (2008/06/13)
Novel preparations comprising branched ligands for the HisB10 Zn2+ sites of the R-state insulin hexamer. The preparations have a prolonged action designed for flexible injection regimes.