364323-77-3

Basic information

• Product Name: Benzaldehyde, 2-(4-bromophenoxy)-
• Synonyms: Benzaldehyde, 2-(4-bromophenoxy)-
• CAS NO: 364323-77-3
• Molecular Weight: 277.117
• Mol File: 364323-77-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 2-(4-bromophenoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 2-(4-bromophenoxy)-(364323-77-3)
• EPA Substance Registry System: Benzaldehyde, 2-(4-bromophenoxy)-(364323-77-3)

Safety Data

• Hazardous Substances Data: 364323-77-3(Hazardous Substances Data)

Upstream product

• 106-41-2 4-bromo-phenol 
• 100-52-7 benzaldehyde 
• 139139-81-4 bis(4-bromophenyl)iodonium triflate 
• 71730-46-6 benzo[e][1,2,3]oxathiazine 2,2-dioxide 
• 552-89-6 2-nitro-benzaldehyde 
• 446-52-6 2-Fluorobenzaldehyde 

Downstream Products

• 2038-92-8 (2-hydroxyphenyl)-(4-bromophenyl)methanone 
• 54313-98-3 2-bromo-9H-xanthene 
• 56341-31-2 2-bromo-9H-xanthene-9-one 

Relevant articles and documents

Formation and Disproportionation of Xanthenols to Xanthenes and Xanthones and Their Use in Synthesis

A facile and versatile strategy employing TiCl4-mediated cyclization followed by a Cannizzaro reaction has been developed for the synthesis of various xanthene derivatives. The reaction proceeded smoothly to afford both xanthenes/xanthones or their sulfur derivatives and tolerated a wide range of electronically diverse substrates. Using this methodology, pranoprofen was synthesized in three steps in 59% overall yield from commercially available starting materials.

Tert -Butoxide mediated cascade desulfonylation/arylation/hydrolysis of cyclic sulfonyimines using diaryliodonium salts: Synthesis of diaryl ether derivatives bearing a 2-aldehyde group

Cascades of cyclic sulfonyimines mediated by tBuOK with diaryliodonium salts has been developed, giving the diaryl ethers in good yields. Furthermore, bulky ortho-substituted diaryl ethers with an aldehyde group can be obtained easily in comparision with metal-catalyzed protocols.

Ligand-free copper-catalyzed O-arylation of nitroarenes with phenols

The first example of ligand-free copper-catalyzed O-arylation of nitroarenes with phenols was developed, achieving unsymmetrical diaryl ethers in moderate to excellent yields. This arylation proceeded smoothly without promotion of the ligands, and displayed great functional group compatibility. Thus, the method represents a new, facile, and cost-effective approach to access unsymmetrical diaryl ethers.