36437-19-1 Usage
Description
2-Chloromalonaldehyde is an organic compound that serves as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals. It is characterized by the presence of a chloro group attached to a malonaldehyde moiety, which provides unique reactivity and functional group compatibility in chemical reactions.
Uses
Used in Pharmaceutical Synthesis:
2-Chloromalonaldehyde is used as a key intermediate for the synthesis of novel heterocyclic acetyl coenzyme-A carboxylase inhibitors. These inhibitors are important in the development of drugs targeting metabolic disorders and lipid synthesis regulation.
Used in Diabetes Treatment:
In the pharmaceutical industry, 2-Chloromalonaldehyde is utilized in the production of aldose reductase inhibitors. These inhibitors play a crucial role in the treatment of diabetes mellitus by reducing the complications associated with hyperglycemia, such as diabetic retinopathy, nephropathy, and neuropathy. The use of 2-Chloromalonaldehyde in the synthesis of these inhibitors contributes to the development of effective therapeutic agents for managing diabetes and its related complications.
Check Digit Verification of cas no
The CAS Registry Mumber 36437-19-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,4,3 and 7 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 36437-19:
(7*3)+(6*6)+(5*4)+(4*3)+(3*7)+(2*1)+(1*9)=121
121 % 10 = 1
So 36437-19-1 is a valid CAS Registry Number.
InChI:InChI=1/C3H3ClO2/c4-3(1-5)2-6/h1-3H
36437-19-1Relevant articles and documents
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Olsen
, p. 544,546 (1948)
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Process for making 2-aryl-3-aryl-5-halo pyridines useful as COX-2 inhibitors
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, (2008/06/13)
The invention encompasses a process for making compounds of Formula I useful in the treatment of cyclooxygenase-2 mediated diseases.