364788-62-5

Basic information

• Product Name: 4-(2,4-dichloro-5-methoxy-phenylamino)-6-(5-formyl-thiophen-3-yl)-quinoline-3-carbonitrile
• CAS NO: 364788-62-5
• Molecular Weight: 454.336
• Mol File: 364788-62-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(2,4-dichloro-5-methoxy-phenylamino)-6-(5-formyl-thiophen-3-yl)-quinoline-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2,4-dichloro-5-methoxy-phenylamino)-6-(5-formyl-thiophen-3-yl)-quinoline-3-carbonitrile(364788-62-5)
• EPA Substance Registry System: 4-(2,4-dichloro-5-methoxy-phenylamino)-6-(5-formyl-thiophen-3-yl)-quinoline-3-carbonitrile(364788-62-5)

Safety Data

• Hazardous Substances Data: 364788-62-5(Hazardous Substances Data)

Upstream product

• 364793-55-5 6-bromo-4-(2,4-dichloro-5-methoxyanilino)-3-quinolinecarbonitrile 
• 364793-52-2 6-bromo-4-oxo-1,4-dihydroquinoline-3-carbonitrile 
• 364793-54-4 6-bromo-4-chloro-3-quinolinecarbonitrile 
• 5794-88-7 5-Bromo-2-aminobenzoic acid 
• 98446-49-2 2,4-dichloro-5-methoxyaniline 

Relevant articles and documents

Inhibition of Src kinase activity by 4-anilino-7-thienyl-3-quinolinecarbonitriles.

Based on a screening lead from a yeast-based assay to identify Src family kinase inhibitors, a series of 4-anilino-7-thienyl-3-quinolinecarbonitriles was prepared. When the thiophene ring was substituted with a water-solubilizing group in a 2,5-, 3,5- or 2,4-pattern, potent inhibition of Src kinase activity was observed.