366-90-5Relevant articles and documents
Synthesis, Biochemistry, and Computational Studies of Brominated Thienyl Chalcones: A New Class of Reversible MAO-B Inhibitors
Mathew, Bijo,Haridas, Abitha,U?ar, Gülberk,Baysal, Ipek,Joy, Monu,Mathew, Githa E.,Lakshmanan, Baskar,Jayaprakash, Venkatesan
, p. 1161 - 1171 (2016/07/14)
A series of (2E)-1-(5-bromothiophen-2-yl)-3-(para-substituted phenyl)prop-2-en-1-ones (TB1–TB11) was synthesized and tested for inhibitory activity toward human monoamine oxidase (hMAO). All compounds were found to be competitive, selective, and reversibl