370102-66-2

Basic information

• Product Name: 6-(4-(methylthio)phenyl)-2,3,6,10b-tetrahydropyrrolo[2,1-a]isoquinolin-5(1H)-one
• Synonyms: 6-(4-(methylthio)phenyl)-2,3,6,10b-tetrahydropyrrolo[2,1-a]isoquinolin-5(1H)-one
• CAS NO: 370102-66-2
• Molecular Weight: 309.432
• Mol File: 370102-66-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6-(4-(methylthio)phenyl)-2,3,6,10b-tetrahydropyrrolo[2,1-a]isoquinolin-5(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(4-(methylthio)phenyl)-2,3,6,10b-tetrahydropyrrolo[2,1-a]isoquinolin-5(1H)-one(370102-66-2)
• EPA Substance Registry System: 6-(4-(methylthio)phenyl)-2,3,6,10b-tetrahydropyrrolo[2,1-a]isoquinolin-5(1H)-one(370102-66-2)

Safety Data

• Hazardous Substances Data: 370102-66-2(Hazardous Substances Data)

Upstream product

• 3446-89-7 4-(Methylthio)benzaldehyde 
• 109086-16-0 2-hydroxy-2-(4-methylthiophenyl)ethanoic acid 
• 93-89-0 benzoic acid ethyl ester 
• 1006-64-0 2-(phenyl)pyrrolidine 
• 700-91-4 2-phenyl-1-pyrroline 
• 125330-79-2 1-[2-hydroxy-2-(4-methylthiophenyl)]ethanoyl-2-phenylpyrrolidine 

Downstream Products

• 1035802-97-1 6-Hydroxy-6-(4-methylsulfanyl-phenyl)-2,3,6,10b-tetrahydro-1H-pyrrolo[2,1-a]isoquinolin-5-one 
• 90390-64-0 trans-1,2,3,5,6,10b-hexahydro-6-<4-(methylthio)phenyl>pyrrolo<2,1-a>isoquinoline 
• 90390-64-0 cis-1,2,3,5,6,10b-hexahydro-6-<4-(methylthio)phenyl>pyrrolo<2,1-a>isoquinoline 
• 120809-07-6 (6S,10bR)-6-(4-Methylsulfanyl-phenyl)-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinolin-6-ol 
• 120809-07-6 (6S,10bS)-6-(4-Methylsulfanyl-phenyl)-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinolin-6-ol 
• 103729-16-4 (+)-McN-5652 

Relevant articles and documents

The structure of McN-5652

The configuration of the diastereoisomers of 6-(4-methylthiophenyl)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline 1 (McN-5652) is determined and unequivocally assigned by NMR spectroscopy (NOE measurements) and an X-ray structural analysis of the trans diastereoisomer. The enantiomers of cis-1 are separated by preparative HPLC on a chiral phase. One of the enantiomers of cis-1 represents the precursor for imaging the serotonin 5-HT transporter with positron emission tomography (PET).