370571-31-6

Basic information

• Product Name: 3-chloro-N-(4-methoxyphenyl)pyridin-2-amine
• Synonyms: 3-chloro-N-(4-methoxyphenyl)pyridin-2-amine;2-AMino-N-(4-Methoxyphenyl)pyridine, 97%
• CAS NO: 370571-31-6
• Molecular Formula: C₁₂H₁₁ClN₂O
• Molecular Weight: 235
• Mol File: 370571-31-6.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-chloro-N-(4-methoxyphenyl)pyridin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloro-N-(4-methoxyphenyl)pyridin-2-amine(370571-31-6)
• EPA Substance Registry System: 3-chloro-N-(4-methoxyphenyl)pyridin-2-amine(370571-31-6)

Safety Data

• Hazardous Substances Data: 370571-31-6(Hazardous Substances Data)

Upstream product

• 2402-77-9 2,3-dichloro-pyridine 
• 104-94-9 4-methoxy-aniline 

Downstream Products

• 78750-82-0 6-methoxy-9H-pyrido[2,3-b]indole 
• 1294517-62-6 N-(4-methoxyphenyl)-3-phenylpyridin-2-amine 

Relevant articles and documents

Synthesis of α-carboline

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One-pot synthesis of α-carbolines via sequential palladium-catalyzed aryl amination and intramolecular arylation

A one-pot synthesis of α-carbolines via a palladium-catalyzed aryl amination followed by intramolecular arylation is described. 2,3-Dichloro- and 2,3-dibromopyridines have been shown to react with readily available anilines to obtain various substituted α-carbolines in moderate to excellent yields.

Selective palladium-catalyzed aminations on dichloropyridines

Palladium-catalyzed amination proved to be a valuable strategy for the selective introduction of aromatic and heteroaromatic amines, including aminopyridines and aminodiazines, on dichloropyridines. The use of mild amination conditions resulted in maximum selectivity and excellent base sensitive functional group tolerance.