37091-33-1 Usage
General Description
1-[3-(4-chlorophenyl)-5-isoxazolyl]-1-ethanone, also known as Etazene, is a synthetic opioid analgesic drug with potent and fast-acting pain-relieving properties. It is structurally similar to fentanyl and is considered to be one of the strongest opioid agonists available. Etazene works by binding to the body's opioid receptors, which are responsible for modulating pain and pleasure sensations. Due to its high potency, Etazene has a high potential for abuse and addiction, and has been associated with several overdose deaths. As a result, it is classified as a controlled substance and is not approved for medical use in most countries.
Check Digit Verification of cas no
The CAS Registry Mumber 37091-33-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,0,9 and 1 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 37091-33:
(7*3)+(6*7)+(5*0)+(4*9)+(3*1)+(2*3)+(1*3)=111
111 % 10 = 1
So 37091-33-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H8ClNO2/c1-7(14)11-6-10(13-15-11)8-2-4-9(12)5-3-8/h2-6H,1H3
37091-33-1Relevant articles and documents
A facile one-pot synthesis of 3,5-disubstituted isoxazole derivatives using hydroxy (tosyloxy) iodobenzene
Jadhav, Ravindra D.,Mistry, Hitesh D.,Motiwala, Hashim,Kadam, Kishorkumar S.,Kandre, Shivaji,Gupte, Amol,Gangopadhyay, Ashok K.,Sharma, Rajiv
, p. 774 - 780 (2013/08/23)
Hydroxy (tosyloxy) iodobenzene (HTIB), a hypervalent iodine reagent, has been extensively used for oxidative transformations. We have developed a one-pot synthesis wherein aldoximes when reacted with alkynes in the presence of HTIB result in the direct formation of isoxazoles. This simple and straightforward reaction allows for ease of purification while leading to the formation of high purity 3,5-disubstituted isoxazoles in moderate yields.
