37091-73-9 Usage
Description
2-Chloro-1,3-dimethylimidazolidinium chloride is a versatile chemical compound with a brown solid appearance, known for its various applications in the synthesis of different organic compounds and as a reagent in various chemical reactions. It acts as an activating agent, dehydrating agent, and is involved in chlorination, oxidation, reduction, and rearrangement processes under nearly neutral conditions.
Uses
1. Used in the Total Synthesis of Complex Molecules:
2-Chloro-1,3-dimethylimidazolidinium chloride is used as an activating agent for the total synthesis of macroviracin A, cycloviracin B1, and cyclic silanes, facilitating the formation of these complex molecules.
2. Used in the Synthesis of Tagged Glucose:
In the field of organic chemistry, 2-Chloro-1,3-dimethylimidazolidinium chloride is used as a reagent for the synthesis of tagged glucose, which serves as an intermediate in the synthesis of branched oligosaccharides.
3. Used in the Development of Fluorescent Chemosensors:
2-Chloro-1,3-dimethylimidazolidinium chloride is utilized in the creation of fluorescent chemosensors, which are essential tools in the detection and analysis of various chemical species.
4. Used as Inhibitors of Co-activator Associated Arginine Methyltransferase 1:
2-Chloro-1,3-dimethylimidazolidinium chloride is used to synthesize 1,2-diamines, which act as inhibitors of co-activator associated arginine methyltransferase 1, playing a role in the regulation of cellular processes.
5. Used in the Synthesis of Allosteric Glucokinase Activators:
It is also employed in the synthesis of allosteric glucokinase activators, which are important in the regulation of glucose metabolism.
6. Used in the Synthesis of Organic Azides from Primary Amines:
2-Chloro-1,3-dimethylimidazolidinium chloride serves as a reactant for the synthesis of organic azides from primary amines, which are crucial intermediates in organic synthesis.
7. Used in Aza-Henry Reactions:
2-Chloro-1,3-dimethylimidazolidinium chloride is used as a reagent in aza-Henry reactions, which are significant in the synthesis of various nitrogen-containing organic compounds.
8. Used as a Powerful Dehydrating Agent:
It can act as a powerful dehydrating agent, replacing DCC (Dicyclohexylcarbodiimide) under nearly neutral conditions, and has applications in the construction of heterocycles.
9. Used in One-pot Synthesis of 2-Aminobenzimidazoles:
2-Chloro-1,3-dimethylimidazolidinium chloride is also applicable to the one-pot synthesis of 2-aminobenzimidazoles, which are important building blocks in the synthesis of various biologically active molecules.
Sources
https://www.sigmaaldrich.com/catalog/product/aldrich/529249?lang=en®ion=US
https://pubs.acs.org/doi/abs/10.1021/jo990210y
www.sciencedirect.com/science/article/pii/S004040391001395X
J. Org. Chem., 1999, 64 (16), pp 5832–5835
Check Digit Verification of cas no
The CAS Registry Mumber 37091-73-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,0,9 and 1 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 37091-73:
(7*3)+(6*7)+(5*0)+(4*9)+(3*1)+(2*7)+(1*3)=119
119 % 10 = 9
So 37091-73-9 is a valid CAS Registry Number.
InChI:InChI=1/C5H10ClN2.ClH/c1-7-3-4-8(2)5(7)6;/h3-4H2,1-2H3;1H/q+1;/p-1
37091-73-9Relevant articles and documents
UEBER STERISCH GEHINDERTE FREIE RADIKALE XI. DIE ERSTE REVERSIBLE THERMISCHE DISSOZIATION VON DISILANEN R3Si-SiR3 ZU SILYLRADIKALEN R3Si. UND VON DIGERMANEN R3Ge-GeR3 ZU GERMYLRADIKALEN R3Ge.
Neumann, Wilhelm P.,Schultz, Klaus-Dieter,Vieler, Robert
, p. 179 - 192 (2007/10/02)
The Si-Si bond in hexamesityldisilane dissociates reversibly even between -60 and -32 deg C (ΔHdiss 19.0 +/- 2 kcal mol-1) and the Ge-Ge bond in hexamesityldigermane reversibly between -12 and +53 deg C (ΔHdiss 20.7 +/- 2
