371244-06-3

Basic information

• Product Name: 2-aMino-6-Methyl-N-o-tolylbenzaMide
• Synonyms: 2-aMino-6-Methyl-N-o-tolylbenzaMide;BenzaMide, 2-aMino-6-Methyl-N-(2-Methylphenyl)-;2-Amino-6-Methyl-N-O-Tolylbenzamide(WX609124)
• CAS NO: 371244-06-3
• Molecular Formula: C₁₅H₁₆N₂O
• Molecular Weight: 240.30034
• Mol File: 371244-06-3.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 2-aMino-6-Methyl-N-o-tolylbenzaMide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-aMino-6-Methyl-N-o-tolylbenzaMide(371244-06-3)
• EPA Substance Registry System: 2-aMino-6-Methyl-N-o-tolylbenzaMide(371244-06-3)

Safety Data

• Hazardous Substances Data: 371244-06-3(Hazardous Substances Data)

Usage

General Description

2-Amino-6-Methyl-N-o-tolylbenzamide is a chemical compound with the molecular formula C16H16N2O. It is an aromatic amine derivative that contains an amino group and a methyl group. 2-aMino-6-Methyl-N-o-tolylbenzaMide is commonly used in organic synthesis and pharmaceutical research as a building block for the development of various drugs and biologically active compounds. It has also been used as a reagent in chemical reactions and serves as a valuable intermediate in the production of other organic compounds. 2-Amino-6-Methyl-N-o-tolylbenzamide may also have potential applications in the field of medicinal chemistry and drug discovery due to its structural properties and biological activity.

Upstream product

• 4389-50-8 2-amino-6-methylbenzoic acid 
• 95-53-4 o-toluidine 

Downstream Products

• 936024-93-0 tert-butyl (S)-1-[3-methyl-2-(o-tolylcarbamoyl)phenylamino]-1-oxopropan-2-ylcarbamate 
• 936024-96-3 tert-butyl (S)-(1-(5-methyl-4-oxo-3-(o-tolyl)-3,4-dihydroquinazolin-2-yl)ethyl)carbamate 
• 936024-94-1 tert-butyl (S)-1-(5-methyl-4-(o-tolylimino)-4H-benzo[d][1,3]oxazin-2-yl)ethylcarbamate 
• 371244-11-0 2-(chloromethyl)-5-methyl-3-(o-tolyl)quinazolin-4(3H)-one 
• 1369877-00-8 PIK-293 
• 371244-07-4 2-(aminomethyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one 
• 1365616-81-4 3-amino-N-{[5-methyl-3-(2-methylphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl]methyl}pyrazine-2-carboxamide 

Relevant articles and documents

Atropisomerism and Conformational Equilibria: Impact on PI3Kδ Inhibition of 2-((6-Amino-9H-purin-9-yl)methyl)-5-methyl-3-(o-tolyl)quinazolin-4(3H)-one (IC87114) and Its Conformationally Restricted Analogs

IC87114 [compound 1, (2-((6-amino-9H-purin-9-yl)methyl)-5-methyl-3-(o-tolyl)quinazolin-4(3H)-one)] is a potent PI3K inhibitor selective for the δ isoform. As predicted by molecular modeling calculations, rotation around the bond connecting the quinazolin-

METHODS AND COMPOSITIONS FOR TREATMENT OF OPHTHALMIC CONDITIONS

The present invention provides chemical entities or compounds and pharmaceutical compositions thereof that are capable of modulating signal transduction by certain protein kinases such as mTor, tyrosine kinases, and/or lipid kinases such as PB kinase in a

Inhibitors of human phosphatidylinositol 3-kinase delta

Methods of inhibiting phosphatidylinositol 3-kinase delta isoform (PI3Kδ) activity, and methods of treating diseases, such as disorders of immunity and inflammation, in which PI3Kδ plays a role in leukocyte function are disclosed. Preferably, the methods employ active agents that selectively inhibit PI3Kδ, while not significantly inhibiting activity of other PI3K isoforms. Compounds are provided that inhibit PI3Kδ activity, including compounds that selectively inhibit PI3Kδ activity. Methods of using PI3Kδ inhibitory compounds to inhibit cancer cell growth or proliferation are also provided. Accordingly, the invention provides methods of using PI3Kδ inhibitory compounds to inhibit PI3Kδ-mediated processes in vitro and in vivo.