3719-84-4Relevant articles and documents
Tungstophosphoric acid/mesoporous silicas as suitable catalysts in quinoxaline synthesis
Langer, Peter,Luque, Rafael,Palermo, Valeria,Pizzio, Luis R.,Romanelli, Gustavo P.,Sosa, Alexis A.
, (2021/12/16)
Quinoxalines and their derivatives are of great value in the chemical and biological sciences. These compounds are found in dyes, agrochemicals, and are used as building blocks of drugs for the treatment of different diseases. Quinoxalines and their deriv
Ultrasound/visible light-mediated synthesis of N-heterocycles using g-C3N4/Cu3TiO4 as sonophotocatalyst
Arunachalapandi, Murugan,Roopan, Selvaraj Mohana
, p. 3363 - 3378 (2021/04/19)
In this investigation, novel g-C3N4/Cu3TiO4 (CNCT) nanocomposite was synthesized by using a simple thermal condensation method. The synthesized CNCT nanocomposite was characterized by X-ray Diffraction, Transmission electron microscopy, Atomic force microscopy, Energy-dispersive X-ray spectroscopy, X-ray photoelectron spectroscopy, UV–vis diffuse reflectance spectroscopy, Photoluminescence, Brunauer–Emmett–Telle, Zeta Potential, and Thermogravimetric analysis. The study revealed that the catalysts prepared have high crystalline nature, optical light-absorbing property, high surface area, and stability. The CNCT- nanocomposite was found to be an extraordinary visible light absorbing catalyst for the synthesis of quinoxaline and quinazolinone derivatives, which have important benefits in a variety of drug applications. Quinoxaline and quinazolinones were prepared from anthranilamide, diamines, benzil, and corresponding aldehydes under Ultrasonic/visible light-medium with a notable amount of g-C3N4/Cu3TiO4. The results exhibit good and excellent yields of product derivatives at mild conditions under Ultrasonic/visible light-medium. Ultrasounds always clean the active site catalyst, promoting activity and reusability. Most notably, with preserved reactivities, this heterogeneous g-C3N4/Cu3TiO4 composite can be used atleast 5 times. Furthermore, we examined the reusability of the catalyst under Ultrasonication coupled with Visible light and in the absence of an Ultrasonication medium. Finally, advantages of the method are non-conventional approach, green solvent, reduced reaction duration, mild condition, and reusable catalyst.
NaOH-Mediated Direct Synthesis of Quinoxalines from o-Nitroanilines and Alcohols via a Hydrogen-Transfer Strategy
Wang, Yan-Bing,Shi, Linlin,Zhang, Xiaojie,Fu, Lian-Rong,Hu, Weinan,Zhang, Wenjing,Zhu, Xinju,Hao, Xin-Qi,Song, Mao-Ping
, p. 947 - 958 (2021/01/14)
A NaOH-mediated sustainable synthesis of functionalized quinoxalines is disclosed via redox condensation of o-nitroamines with diols and α-hydroxy ketones. Under optimized conditions, various o-nitroamines and alcohols are well tolerated to generate the desired products in 44-99% yields without transition metals and external redox additives.