371945-23-2

Basic information

• Product Name: Pyrido[3',2':4,5]furo[3,2-d]pyriMidin-4(3H)-one, 2-[3-(acetyloxy)phenyl]-
• Synonyms: Pyrido[3',2':4,5]furo[3,2-d]pyriMidin-4(3H)-one, 2-[3-(acetyloxy)phenyl]-;3-(4-Oxo-3,4-dihydropyrido[3,2:4,5]furo[3,2-d]pyrimidin-2-yl)phenyl acetate
• CAS NO: 371945-23-2
• Molecular Formula: C₁₇H₁₁N₃O₄
• Molecular Weight: 321.28694
• Mol File: 371945-23-2.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Pyrido[3',2':4,5]furo[3,2-d]pyriMidin-4(3H)-one, 2-[3-(acetyloxy)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrido[3',2':4,5]furo[3,2-d]pyriMidin-4(3H)-one, 2-[3-(acetyloxy)phenyl]-(371945-23-2)
• EPA Substance Registry System: Pyrido[3',2':4,5]furo[3,2-d]pyriMidin-4(3H)-one, 2-[3-(acetyloxy)phenyl]-(371945-23-2)

Safety Data

• Hazardous Substances Data: 371945-23-2(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 371945-16-3 2-(3-methoxyphenyl)pyrido[3′,2′:4,5]furo[3,2-d]pyrimidin-4(3H)-one 
• 371945-06-1 3-amino-furo[2,3-b]pyridine-2-carboxylic acid ethyl ester 
• 371943-69-0 ethyl 3-(3-methoxybenzamido)furo[2,3-b]pyridine-2-carboxylate 
• 371943-84-9 C₁₆H₁₂N₂O₅ 
• 371944-46-6 3-(3-methoxybenzamido)furo[2,3-b]pyridine-2-carboxamide 
• 6602-54-6 2-chloro-3-pyridinecarbonitrile 
• 1711-05-3 m-anisoyl chloride 

Downstream Products

• 371935-74-9 3-(4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl)phenol 
• 697736-71-3 C₂₃H₂₂N₄O₅ 

Relevant articles and documents

Development of a bioavailable boron-containing PI-103 Bioisostere, PI-103BE

PI-103 (7) is a potent dual phosphatidylinositol 3-kinase (PI3K)/mTOR inhibitor, but its rapid in vivo metabolism hinders its further clinical development. To improve the bioavailability of PI-103, we designed and synthesized a PI-103 bioisostere, PI-103B