373380-62-2

Basic information

• Product Name: 2-bromo-1-(methoxymethoxy)-4-nitrobenzene
• Synonyms: 2-bromo-1-(methoxymethoxy)-4-nitrobenzene
• CAS NO: 373380-62-2
• Molecular Weight: 262.06
• Mol File: 373380-62-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-bromo-1-(methoxymethoxy)-4-nitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-1-(methoxymethoxy)-4-nitrobenzene(373380-62-2)
• EPA Substance Registry System: 2-bromo-1-(methoxymethoxy)-4-nitrobenzene(373380-62-2)

Safety Data

• Hazardous Substances Data: 373380-62-2(Hazardous Substances Data)

Upstream product

• 5847-59-6 2-bromo-4-nitrophenol 
• 107-30-2 chloromethyl methyl ether 

Downstream Products

• 1592683-74-3 2-[2-(methoxymethoxy)-5-nitrophenyl]-1-tetralone 
• 1355680-36-2 C₁₂H₁₆N₂O₅ 
• 1355685-80-1 C₂₅H₂₈N₄O₅S 
• 1355685-79-8 C₂₅H₂₆N₄O₇S 
• 1355680-37-3 C₁₁H₁₁F₃N₂O₆S 
• 474454-63-2 1-(5-amino-2-hydroxy)phenyl-4-phenylbutyne 
• 474454-67-6 2-[(1E)-4phenylbut-1-enyl]-4-aminophenol 
• 474454-64-3 cis-1-(5-amino-2-hydroxy)phenyl-4-phenylbutene 
• 474454-66-5 1-methoxymethoxy-2-[(1E)-4-phenylbut-1-eney]-4-nitrobenzene 
• 474454-62-1 1-(2-methoxymethoxy-5-nitro)phenyl-4-phenylbutyne 

Relevant articles and documents

A study of enantioselective syntheses by Sharpless asymmetric oxidation for aryl sulfoxides containing oxygen groups at the ortho position

Abstract: While ortho-alkoxy aryl sulfoxides including various substituents were synthesized by Sharpless asymmetric oxidation reaction, we optimized the reaction conditions and screened better combination of starting materials to obtain high enantioselectivity. The result suggested new information that electron-withdrawing substituents on the aromatic ring have a strong influence upon enantioselectivity of the products. Also, several chiral ligands for Sharpless asymmetric oxidation reaction were evaluated to improve the enantioselectivity. Graphic abstract: High enantioselectivity of ortho-alkoxy aryl chiral sulfoxides have been achieved by Sharpless oxidation reaction using Ti(O-i-Pr)4 and diethyl tartrate under anhydrous condition. In particular, the enantioselctivity of products was influenced by electron-withdrawing substituents on the aromatic ring, such as nitro, ester and aldehyde groups.[Figure not available: see fulltext.]

Synthesis and investigation of conformationally restricted analogues of lavendustin A as cytotoxic inhibitors of tubulin polymerization

A series of conformationally restricted analogues were synthesized in order to elucidate the possible effects of different amide conformations of lavendustin A derivatives on cytotoxicity in cancer cell cultures and on inhibition of tubulin polymerization. The conformationally restricted analogues were based on the oxazinedione and isoindolone ring systems. In addition, the amide bond was replaced by both cis and trans alkene moieties. Surprisingly, the results indicated very little effect of conformational restriction on biological activity. Because all of the compounds synthesized had similar cytotoxicities and potencies as tubulin polymerization inhibitors, the side chain present on the aniline ring system does not appear to be important in the biological effects of the lavendustins. The hydroquinone ring of lavendustin A may be a more important determinant of the biological activity than the structure surrounding the aniline ring.

p-aminophenol derivative compounds and dye compositions containing same

The p-aminophenol derivative compounds of formula (1), or their physiologically compatible water-soluble salts: 1are useful as developer compounds in oxidation dye compositions for keratin fibers. Oxidation dye compositions for keratin fibers, including hair, and methods of dyeing hair using the p-aminophenol derivative compounds are also described.