374813-35-1

Basic information

• Product Name: 1H-2-Benzazepin-8-ol, 2,3,4,5-tetrahydro-, hydrobromide
• CAS NO: 374813-35-1
• Molecular Formula: C10H13NO.BrH
• Mol File: 374813-35-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1H-2-Benzazepin-8-ol, 2,3,4,5-tetrahydro-, hydrobromide(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-2-Benzazepin-8-ol, 2,3,4,5-tetrahydro-, hydrobromide(374813-35-1)
• EPA Substance Registry System: 1H-2-Benzazepin-8-ol, 2,3,4,5-tetrahydro-, hydrobromide(374813-35-1)

Safety Data

• Hazardous Substances Data: 374813-35-1(Hazardous Substances Data)

Usage

Class

Benzazepines

Biological Activity

Significant

Common Uses

Pharmaceutical drug for treating neurological and psychiatric disorders (e.g. depression, anxiety)

Salt Form

Hydrobromide

Benefits of Salt Form

Increased solubility and stability

Solubility

Improved

Stability

Improved

Effectiveness

Enhanced

Upstream product

• 860436-55-1 8-methoxy-2,3,4,5-tetrahydro-1H-2-benzazepine hydrochloride 
• 22246-71-5 8-methoxy-2,3,4,5-tetrahydro-1H-2-benzazepin-1-one 
• 247133-22-8 8-Methoxy-2,3,4,5-tetrahydro-1H-benz[c]azepine 

Relevant articles and documents

AMIDINE DERIVATIVE

Provision of a novel amidine derivative or a pharmaceutically acceptable salt thereof having an activated blood coagulation factor X-inhibitory activity. A compound represented by the formula (I) wherein each symbol is as defined above, or a pharmaceutically acceptable salt thereof.

Synthesis and structure-activity relationships of novel selective factor Xa inhibitors with a tetrahydroisoquinoline ring

A series of novel 2,7-disubstituted tetrahydroisoquinoline derivatives were designed and synthesized. Among these derivatives, compounds 1 and 2 exhibited potent inhibitory activity against factor Xa (FXa) and good selectivity with respect to other serine

Amidine compounds

A compound of the formula [I] wherein R1, R2and R3are the same or different and each is hydrogen atom, wherein each symbol is as defined in the specification, a salt thereof or a prodrug thereof. The compound of the presen