375372-32-0

Basic information

• Product Name: Diethyl [(2-isocyanophenyl)methyl]phosphonate
• Synonyms: Diethyl [(2-isocyanophenyl)methyl]phosphonate
• CAS NO: 375372-32-0
• Molecular Weight: 253.238
• Mol File: 375372-32-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Diethyl [(2-isocyanophenyl)methyl]phosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: Diethyl [(2-isocyanophenyl)methyl]phosphonate(375372-32-0)
• EPA Substance Registry System: Diethyl [(2-isocyanophenyl)methyl]phosphonate(375372-32-0)

Safety Data

• Hazardous Substances Data: 375372-32-0(Hazardous Substances Data)

Upstream product

• 4914-12-9 diethyl 2-nitrobenzylphosphonate 
• 3958-60-9 2-nitrophenylmethyl bromide 
• 552-89-6 2-nitro-benzaldehyde 
• 79202-15-6 diethyl (hydroxy)(2-nitrophenyl)methylphosphonate 

Downstream Products

• 375372-37-5 3-pentyl-2-phenylsulfanyl-1H-indole 
• 1027208-32-7 3-cyclohexyl-2-ethylsulfanyl-1H-indole 
• 100717-32-6 3-cyclohexyl-1H-indole 

Relevant articles and documents

A novel protocol for construction of indolylmethyl group at aldehydes or ketones

A new method for introduction of indolylmethyl group to aldehydes or ketones using diethyl (o-isocyanophenylmethyl) phosphonate through Horner-Wadsworth-Emmons condensation, thiolmediated radical cyclization, and the subsequent desulfurization is described. The Horner-Wadsworth-Emmons reagent was prepared from 2-nitrobenzaldehyde in a concise three-step sequence.