37892-44-7

Basic information

• Product Name: 2-azido-4'-bromo-benzophenone
• Synonyms: 2-azido-4'-bromo-benzophenone
• CAS NO: 37892-44-7
• Molecular Weight: 302.13
• Mol File: 37892-44-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-azido-4'-bromo-benzophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-azido-4'-bromo-benzophenone(37892-44-7)
• EPA Substance Registry System: 2-azido-4'-bromo-benzophenone(37892-44-7)

Safety Data

• Hazardous Substances Data: 37892-44-7(Hazardous Substances Data)

Upstream product

• 18620-02-5 (4-bromophenyl)magnesium bromide 
• 525-76-8 2-methyl-4-oxo-3,1-benzoxazine 
• 1140-17-6 2-amino-4'-bromobenzophenone 
• 108-86-1 bromobenzene 
• 118-92-3 anthranilic acid 
• 6311-23-5 2-(toluene-4-sulfonylamino)-benzoic acid 

Downstream Products

• 1140-36-9 3-(4-bromophenyl)benzo[c]isoxazole 

Relevant articles and documents

Gold-catalyzed cyclization of 1-(2′-Azidoaryl) propynols: Synthesis of polysubstituted 4-quinolones

An unprecedented gold-catalyzed procedure for the synthesis of polysubstituted 4-quinolones from 1-(2′-Azidoaryl) propynols is described. The reaction undergoes an intramolecular nucleophilic attack of the azide group to the Au-Activated triple bonds in a 6-endo-dig manner and subsequent gold-Assisted expulsion of N2 to furnish an α-imino gold carbene intermediate, which triggers a 1,2-carbon migration and finally is converted to 2,3-disubstituted 4-quinolone.

An In-depth Study of the Azidobenzophenone-Anthranil-Acridone Transformation

The title transformation, particularly the conversion of anthranils into acridones, is shown to be critically sensitive to temperature, solvent, substituent, and metal catalysts.Thus the conversion of 3-(p-tolyl)anthranil into an acridone gives a ratio of 2-and 3-methyl derivatives varying from 0.6:1 to 4.7:1 with changing temperature and solvent.In other similar thermolyses, solvents (e.g. 1,2,4-trichlorobenzene) were incorporated into the product and traces of metals and their derivatives had a dramatic effect on the rate and course of the reaction.The most effective catalysts were iron powder and aluminium acetylacetonate. 3-(2,6-Disubstituted phenyl)anthranils gave acridones in which the substituents were either lost or rearranged onto N or C, the last cases involving sequential -sigmatropic shifts. 3-Thienylanthranils gave related thienoquinolones on thermolysis; again the reaction were very sensitive to catalysis.Blocked thienylanthranils also gave rearrangement products, but the non-aromatic intermediates could be isolated.