1140-17-6

Basic information

• Product Name: 2-AMINO-4'-BROMOBENZOPHENONE
• Synonyms: (2-AMINO-PHENYL)-(4-BROMO-PHENYL)-METHANONE;Methanone,(2-aMinophenyl)(4-broMophenyl)-;-bromobenzophenone
• CAS NO: 1140-17-6
• Molecular Formula: C₁₃H₁₀BrNO
• Molecular Weight: 276.13
• Product Categories: Aromatic Benzophenones & Derivatives (substituted)
• Mol File: 1140-17-6.mol
• Article Data: 23

Chemical Properties

• Melting Point: 103-110 °C
• Boiling Point: 432.5±25.0 °C(Predicted)
• Appearance: /
• Density: 1.484±0.06 g/cm3 (20 ºC 760 Torr)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: -0.36±0.10(Predicted)
• CAS DataBase Reference: 2-AMINO-4'-BROMOBENZOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-4'-BROMOBENZOPHENONE(1140-17-6)
• EPA Substance Registry System: 2-AMINO-4'-BROMOBENZOPHENONE(1140-17-6)

Safety Data

• Hazard Codes: Xi,N
• Statements: 43-51/53
• Safety Statements: 36/37-61
• RIDADR: UN 3077 9/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 1140-17-6(Hazardous Substances Data)

Usage

General Description

2-AMINO-4'-BROMOBENZOPHENONE, also known as 4'-Bromo-2-aminobenzophenone, is a chemical compound with the molecular formula C13H10BrNO. It is a benzophenone derivative with a bromine atom at the 4' position and an amino group at the 2 position. 2-AMINO-4'-BROMOBENZOPHENONE is commonly used as a photoinitiator in the production of light-curable materials like adhesives, inks, coatings, and dental composites. It also has potential applications in the field of organic electronics and pharmaceuticals. However, its use may be restricted and regulated due to its potential toxicity and environmental impacts.

Upstream product

• 2059-99-6 2-(4-bromo-benzoyl)-benzoic acid amide 
• 118667-16-6 4-bromo-benzophenone-(E)-oxime 
• 108-86-1 bromobenzene 
• 42840-02-8 2-(Toluene-4-sulfonylamino)-benzoyl chloride 
• 525-76-8 2-methyl-4-oxo-3,1-benzoxazine 
• 589-87-7 1,4-bromoiodobenzene 
• 6311-23-5 2-(toluene-4-sulfonylamino)-benzoic acid 
• 42156-66-1 3-(4-bromophenyl)-3-hydroxy-2,3-dihydro-1H-isoindol-1-one 
• 370851-82-4 2-(4-bromobenzoyl)-1-(4-methylphenylsulfonamido)benzene 
• 118-92-3 anthranilic acid 
• 861781-61-5 (2-nitrophenyl)(4-bromophenyl)methanone 
• 85-44-9 phthalic anhydride 
• 1264292-44-5 2-(4-bromobenzoyl)benzoyl azide 
• 2159-40-2 2-(4-bromobenzoyl)benzoic acid 

Downstream Products

• 102703-55-9 N-[2-(4-bromo-benzoyl)-phenyl]-phthalimide 
• 37892-44-7 2-azido-4'-bromo-benzophenone 
• 500870-79-1 2-N-(4-methylsulfonylbenzoyl)-amide-4'-bromo-benzophenone 
• 500870-80-4 2-N-(4-aminosulfonylbenzoyl)-amide-4'-bromo-benzophenone 
• 370851-82-4 2-(4-bromobenzoyl)-1-(4-methylphenylsulfonamido)benzene 
• 373618-56-5 2-[4-bromophenyl(hydroxy)methyl]-1-(4-methylphenylsulfonamido)benzene 
• 374541-52-3 2-[4-bromophenyl(5-methyl-2-furyl)methyl]-1-(4-methylphenylsulfonamido)benzene 
• 374606-77-6 4-[3-(4-bromophenyl)-1-(4-methylphenylsulfonyl)-1H-2-indolyl]-2-butanone 
• 91409-73-3 2-[2-(4-Bromo-benzoyl)-phenylamino]-propionic acid 
• 91713-90-5 7-(4-Bromo-benzoyl)-3-methylsulfanyl-1,3-dihydro-indol-2-one 
• 1140-36-9 3-(4-bromophenyl)benzo[c]isoxazole 
• 1010690-99-9 syn-(2-aminophenyl)(4-bromophenyl)methanone oxime 
• 1242185-14-3 (R)-tert-butyl 4-(2-(4-bromobenzoyl)phenylcarbamoyl)-2,2-dimethyloxazolidine-3-carboxylate 
• 1291080-09-5 4-(4-bromophenyl)-3-iodo-2-phenylquinoline 

Relevant articles and documents

Palladium-catalyzed direct addition of 2-Aminobenzonitriles to sodium arylsulfinates: Synthesis of o-Aminobenzophenones

The first example of the palladium-catalyzed synthesis of o-Aminobenzophenones in moderate to excellent yields via a direct addition of sodium arylsulfinates to unprotected 2-Aminobenzonitriles was reported. A plausible mechanism for the formation of o-Aminobenzophenones involving desulfination and addition reactions was proposed. The utility of this transformation was demonstrated by its compatibility with a wide range of functional groups. Thus, the method represents a convenient and practical strategy for synthesis of o-Aminobenzophenones.

Benzene type liquid crystal compound and preparation method thereof

The invention relates to the technical field of liquid crystal compounds, in particular to a benzene liquid crystal compound and a preparation method thereof, wherein the benzene type liquid crystal compound is N. 4 , N4 , N4 ’ , N4 ’ - (9, 9 - Diphenyl - 9H - fluorene -3 - yl) -2 - methyl - [1, 1 ’ - biphenyl] -4, 4 ’ - diamine, the preparation method of the benzene type liquid crystal compound is that 2 - nitrobenzoic acid is used as a starting material to react with oxalyl chloride to obtain 2 - nitrobenzoyl chloride. The reaction was again reacted with bromobenzene to give (4 - bromophenyl) (2 - nitrophenyl) methyl ketone. The reduction reaction is followed by obtaining (4 - bromophenyl) (2 - aminophenyl) methyl ketone. The 3 - bromo - 9H - fluorene -9 - ketone is obtained by using sulfuric acid and sodium nitrite as a catalyst. The Grignard reagent of bromobenzene is reacted again to obtain 3 - bromo -9, 9 - diphenyl - 9H - fluorene. Reaction with cuprous iodide gives 3 - iodine -9, 9 - diphenyl - 9H - fluorene. 2 - Methyl - [1, 1 ’ - biphenyl] -4, 4 ’ - diamine was prepared, and then reacted with 3 - iodine -9, 9 - diphenyl - 9H - fluorene to obtain the benzene-based liquid crystal compound of the present invention. The invention can be applied to preparation of liquid crystal mixtures, liquid crystal display device materials or electro-optical display device materials.

Experimental and Computational Studies on Cp*CyRh(III)/KOPiv-Catalyzed Intramolecular Dehydrogenative Cross-Couplings for Building Eight-Membered Sultam/Lactam Frameworks

Described herein is an unusual Cp*CyRh(III)-catalyzed intramolecular site-specific aryl C-H annulation, a highly chemoselective protocol providing direct access to eight-membered sultams/lactams with broad substrate/functional group tolerance. Experimental and computational studies reveal that such a transformation involves a unique PivOH-assisted aryl C-H activation/alkene insertion/β-H elimination/hydrogen-transfer process involving the Rh(III)-hydride species as the active intermediate with the concomitant release of H2 as the major byproduct, thus enabling the developed Cp*CyRh(III) catalysis with redox-neutral and highly atom-economical features.

Method for catalytically synthesizing Bronuck intermediate 2-amino-4'-bromo-benzophenone

The invention relates to a method for catalytically synthesizing a Bronuck intermediate 2-amino-4'-bromo-benzophenone. The method comprises the following steps: catalytic promotion is carried out by using Bronsted acid in the presence of a nickel catalyst, and o-aminobenzonitrile reacts with p-bromophenylboronic acid in a mixed solvent, so that the 2-amino-4'-bromo-benzophenone is obtained. According to the method, through comprehensive selection of a suitable reaction system, a plurality of defects existing in the prior art are overcome, and particularly serious defects that products cannot be obtained are overcome, so that easy-to-obtain raw materials are provided for synthesis of Bronuck, and therefore, the method has remarkable economic values and application potentials in the field of medicine synthesis of the Bronuck.