861781-61-5

Basic information

• Product Name: (2-nitrophenyl)(4-bromophenyl)methanone
• Synonyms: (2-nitrophenyl)(4-bromophenyl)methanone
• CAS NO: 861781-61-5
• Molecular Weight: 306.115
• Mol File: 861781-61-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (2-nitrophenyl)(4-bromophenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2-nitrophenyl)(4-bromophenyl)methanone(861781-61-5)
• EPA Substance Registry System: (2-nitrophenyl)(4-bromophenyl)methanone(861781-61-5)

Safety Data

• Hazardous Substances Data: 861781-61-5(Hazardous Substances Data)

Upstream product

• 108-86-1 bromobenzene 
• 612-23-7 2-nitrobenzyl chloride 
• 552-16-9 ortho-nitrobenzoic acid 
• 610-14-0 2-nitrobenzyl chloride 

Downstream Products

• 1140-17-6 2-amino-4'-bromobenzophenone 
• 1547491-70-2 3-bromo-9,9-diphenyl-9H-fluorene 
• 1332696-79-3 4-(para-bromo)phenylquinazoline 
• 861342-27-0 4'-bromo-2,3'-dinitro-benzophenone 

Relevant articles and documents

Benzene type liquid crystal compound and preparation method thereof

The invention relates to the technical field of liquid crystal compounds, in particular to a benzene liquid crystal compound and a preparation method thereof, wherein the benzene type liquid crystal compound is N. 4 , N4 , N4 ’ , N4 ’ - (9, 9 - Diphenyl - 9H - fluorene -3 - yl) -2 - methyl - [1, 1 ’ - biphenyl] -4, 4 ’ - diamine, the preparation method of the benzene type liquid crystal compound is that 2 - nitrobenzoic acid is used as a starting material to react with oxalyl chloride to obtain 2 - nitrobenzoyl chloride. The reaction was again reacted with bromobenzene to give (4 - bromophenyl) (2 - nitrophenyl) methyl ketone. The reduction reaction is followed by obtaining (4 - bromophenyl) (2 - aminophenyl) methyl ketone. The 3 - bromo - 9H - fluorene -9 - ketone is obtained by using sulfuric acid and sodium nitrite as a catalyst. The Grignard reagent of bromobenzene is reacted again to obtain 3 - bromo -9, 9 - diphenyl - 9H - fluorene. Reaction with cuprous iodide gives 3 - iodine -9, 9 - diphenyl - 9H - fluorene. 2 - Methyl - [1, 1 ’ - biphenyl] -4, 4 ’ - diamine was prepared, and then reacted with 3 - iodine -9, 9 - diphenyl - 9H - fluorene to obtain the benzene-based liquid crystal compound of the present invention. The invention can be applied to preparation of liquid crystal mixtures, liquid crystal display device materials or electro-optical display device materials.

A simple and efficient approach to the synthesis of 2-phenylquinazolines via sp3 C-H functionalization

(Figure presented) A facile and novel approach to the synthesis of 2-phenylquinazolines was developed via a tandem reaction following sp 3 C-H functionalization. Twenty-five examples of 2-phenylquinazolines were obtained from easily available 2-aminobenzophenones and benzylic amines with good to excellent yields.

A practical, metal-free synthesis of 1H-Lndazoles

The synthesis of 1H-indazoles is achieved from o-aminobenzoximes by the selective activation of the oxime in the presence of the amino group. The reaction occurs with a variety of substituted o-aminobenzoximes using a slight excess of methanesulfonyl chloride and triethylamine at 0-23 °C and is amenable to scale-up. The synthesis of 1 H-indazoles under these conditions is extremely mild compared with previous synthetic approaches and affords the desired compounds in good to excellent yields.