38010-47-8

Basic information

• Product Name: (E)-3-Hydroxy-2,2,3-trimethyl-5-phenyl-pent-4-enenitrile
• CAS NO: 38010-47-8
• Molecular Weight: 215.295
• Mol File: 38010-47-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-3-Hydroxy-2,2,3-trimethyl-5-phenyl-pent-4-enenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-Hydroxy-2,2,3-trimethyl-5-phenyl-pent-4-enenitrile(38010-47-8)
• EPA Substance Registry System: (E)-3-Hydroxy-2,2,3-trimethyl-5-phenyl-pent-4-enenitrile(38010-47-8)

Safety Data

• Hazardous Substances Data: 38010-47-8(Hazardous Substances Data)

Upstream product

• 41658-69-9 2-bromo-2-methyl-propionitrile 
• 5650-07-7 3-methyl-1-phenyl-but-2-en-1-one 

Relevant articles and documents

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Organozinc compounds derived from α-bromonitriles are readily prepared in solution in tetrahydrofuran (THF) and exist in the C metallated form. They condense normally with aldehydes and saturated ketones. A number of new β-hydroxy-nitriles are described. The addition of conjugated unsaturated ketones results in the formation of β-hydroxynitriles or ketonitriles, depending on the nature of the initial bromonitrile. The stereochemistry of the reaction of benzaldehyde with zinc-α-bromonitrile is not influenced by the nature of the solvent. Condensation with diethyl-malonate alkylidenes lead to the expected 1,4-addition products.