384793-16-2

Basic information

• Product Name: (2-bromo-4-chloro-phenyl)-carbamic acid tert-butyl ester
• Synonyms: (2-bromo-4-chloro-phenyl)-carbamic acid tert-butyl ester
• CAS NO: 384793-16-2
• Molecular Weight: 306.587
• Mol File: 384793-16-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (2-bromo-4-chloro-phenyl)-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2-bromo-4-chloro-phenyl)-carbamic acid tert-butyl ester(384793-16-2)
• EPA Substance Registry System: (2-bromo-4-chloro-phenyl)-carbamic acid tert-butyl ester(384793-16-2)

Safety Data

• Hazardous Substances Data: 384793-16-2(Hazardous Substances Data)

Usage

General Description

(2-bromo-4-chloro-phenyl)-carbamic acid tert-butyl ester, also known as bromocarbumide, is a chemical compound with the molecular formula C10H11BrClNO2. It is a carbamate insecticide that is used for controlling a wide range of pests, including insects and mites, on various crops. Bromocarbumide works by inhibiting the activity of acetylcholinesterase, an enzyme that is essential for the proper functioning of the nervous system in insects. This disruption leads to paralysis and eventual death of the pests. However, due to its toxic nature, bromocarbumide should be handled and used with caution, as it can have harmful effects on non-target organisms and the environment.

Upstream product

• 880384-41-8 N,N-di-tert-butyloxycarbonyl-2-bromo-4-chloroaniline 
• 873-38-1 4-chloro-2-bromoaniline 
• 24424-99-5 di-tert-butyl dicarbonate 
• 18437-66-6 N-(t-butoxycarbonyl)-4-chloroaniline 

Downstream Products

• 1440672-59-2 N-(2-bromo-4-chlorophenyl)-N-tert-butoxycarbonylphenylethynylamine 
• 719-64-2 5-chloro-3-phenylanthranil 
• 1333120-11-8 tert-butyl (2-bromo-4-chlorophenyl)(2-methylallyl)carbamate 
• 1186637-27-3 N-(tert-butoxycarbonyl)-4-chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline 

Relevant articles and documents

Solvent-free, uncatalyzed asymmetric "ene" reactions of: N-Tert-butylsulfinyl-3,3,3-Trifluoroacetaldimines: A general approach to enantiomerically pure α-(trifluoromethyl)tryptamines

A novel approach to regioselectively substituted and stereoselectively α-Trifluoromethylated tryptamines is reported based on the ene reaction of Boc-protected 3-methyleneindolines with optically pure (R)-or (S)-Tert-butanesulfinyltrifluoroacetaldimine. B

Palladium-catalyzed annulation of haloanilines and halobenzamides using norbornadiene as an acetylene synthon: A route to functionalized indolines, isoquinolinones, and indoles

A general procedure for the palladium-catalyzed annulation of substituted haloanilines with norbornadiene gives functionalized indolines in 51-98% yield. These indolines can be rapidly converted to benzenoid- substituted indoles and tricyclic indolines. Extension to the use of substituted halobenzamides gives functionalized isoquinolinones in up to 86% yield.

An improved synthesis of N-Boc protected aryl amines

There are several known methods of protecting amines as their Boc derivatives. For less nucleophilic amines such as aryl amines these methods often give poor yields and are generally not satisfactory. Here, Boc aryl amines are obtained by first introducing two Boc groups followed by selective removal of one of them. This procedure works well for a number highly sterically hindered substrates as well as electron deficient and electron rich aryl amines.