38527-51-4

Basic information

• Product Name: 7-nitro-2-phenyl-4H-benzo[d][1,3]oxazin-4-one
• Synonyms: 7-nitro-2-phenyl-4H-benzo[d][1,3]oxazin-4-one
• CAS NO: 38527-51-4
• Molecular Weight: 268.229
• Mol File: 38527-51-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 7-nitro-2-phenyl-4H-benzo[d][1,3]oxazin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7-nitro-2-phenyl-4H-benzo[d][1,3]oxazin-4-one(38527-51-4)
• EPA Substance Registry System: 7-nitro-2-phenyl-4H-benzo[d][1,3]oxazin-4-one(38527-51-4)

Safety Data

• Hazardous Substances Data: 38527-51-4(Hazardous Substances Data)

Upstream product

• 1663-61-2 triethoxymethylbenzene 
• 619-17-0 4-Nitroanthranilic acid 
• 98-88-4 benzoyl chloride 
• 128054-13-7 4-Nitro-2-(triphenylphosphoranylidenamino)benzoesaeure-methylester 
• 4993-89-9 2-benzoylamino-4-nitro-benzoic acid 

Downstream Products

• 92061-25-1 3-amino-7-nitro-2-phenyl-3H-quinazolin-4-one 
• 1179529-73-7 3-{[(2-seleno-7-methoxyquinolin-3-yl)methylene]amino}-7-nitro-2-phenylquinazolin-4(3H)-one 
• 1179529-68-0 3-{[(2-mercapto-7-methoxyquinolin-3-yl)methylene]amino}-7-nitro-2-phenylquinazolin-4(3H)-one 
• 1179529-64-6 3-{[(2-chloro-7-methoxyquinolin-3-yl)methylene]amino}-7-nitro-2-phenylquinazolin-4(3H)-one 
• 65-85-0 benzoic acid 
• 619-17-0 4-Nitroanthranilic acid 
• 77995-28-9 [4-(7-Nitro-4-oxo-2-phenyl-4H-quinazolin-3-yl)-phenylsulfanyl]-acetic acid 

Relevant articles and documents

4H-Benzo[d][1,3]oxazin-4-ones and Dihydro analogs from substituted anthranilic acids and orthoesters

A one-pot route to 2-alkyl and 2-aryl-4H-benzo[d][1,3]oxazin-4-ones (also known as 4H-3,1-benzoxazin-4-ones) has been developed and studied. The method involves the reaction of aryl-substitutedanthranilic acidswithorthoesters inethanol catalyzedby acetic acid. Additionally,wehave also investigated the reaction under microwave conditions. Not all of the substrates were successful in yielding the target heterocycles as some of the reactions failed to undergo the final elimination. This process led to the isolation of (±)-2-alkyl/aryl-2-ethoxy-1,2-dihydro-4H-benzo[d][1,3]oxazin-4-ones. The formation of the dihydro analogs correlated with the electron density on the aromatic ring: Electron-donating groups favored the 4H- benzo[d][1,3]oxazin-4-ones, while electron-withdrawing groups tended to favor the dihydro product. Substituting a pyridine ring for the benzene ring in the substrate acid suppressed the reaction.

Synthesis of quinoline-based thieno-seleno-phenylquinazolinones

The synthesis of quinoline-substituted phenylquinazolinones containing sulfur and selenium is described. These molecules were isolated from a series of reactions of 2-phenyl-4H-3,1-benzoxazin-4-one with 2-chloro, 2-thieno, and 2-selenoquinoline-3-carbalde

Potential biologically active agents, XXVII: Synthesis of some 4-substituted phenylmercaptoacetic acids

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