386747-26-8

Basic information

• Product Name: (R)-2-Phenyl-2-((R)-1-phenyl-but-3-enylamino)-acetamide
• Synonyms: (R)-2-Phenyl-2-((R)-1-phenyl-but-3-enylamino)-acetamide
• CAS NO: 386747-26-8
• Molecular Weight: 280.37
• Mol File: 386747-26-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-2-Phenyl-2-((R)-1-phenyl-but-3-enylamino)-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-Phenyl-2-((R)-1-phenyl-but-3-enylamino)-acetamide(386747-26-8)
• EPA Substance Registry System: (R)-2-Phenyl-2-((R)-1-phenyl-but-3-enylamino)-acetamide(386747-26-8)

Safety Data

• Hazardous Substances Data: 386747-26-8(Hazardous Substances Data)

Upstream product

• 18925-10-5 allylzinc bromide 
• 741681-30-1 (R)-2-[(phenylmethylene)amino]-2-phenylacetamide 
• 106-95-6 allyl bromide 
• 700-63-0 (R)-phenylglycine amide 
• 100-52-7 benzaldehyde 

Downstream Products

• 2941-19-7 (R)-1-phenylbutylamine 
• 569671-27-8 Phenyl-((R)-1-phenyl-but-3-enylamino)-acetonitrile 
• 115224-13-0 (R)-4-amino-4-phenyl-1-butene 
• 4383-23-7 (S)-1-phenylbut-3-en-1-amine 
• 104-51-8 1-butylbenzene 

Relevant articles and documents

Synthesis of enantiopure 1-aryl-1-butylamines and 1-aryl-3-butenylamines by diastereoselective addition of allylzinc bromide to imines derived from (R)-phenylglycine amide

The synthesis of enantiopure 1-aryl-1-butylamines via a highly diastereoselective addition of allylzinc bromide to imines derived from (R)-phenylglycine amide is reported. These are synthesised by a three-step procedure, which involves: (a) formation of the chiral imines; (b) asymmetric addition of the allylzinc reagent; (c) removal of the chiral auxiliary by means of a reductive or non-reductive method. The reductive method provides 1-aryl-1-butylamines whereas the non-reductive method preserves the double bond to afford 1-aryl-3-butenylamines. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.