741681-30-1

Basic information

• Product Name: (R)-2-[(phenylmethylene)amino]-2-phenylacetamide
• Synonyms: (R)-2-[(phenylmethylene)amino]-2-phenylacetamide
• CAS NO: 741681-30-1
• Molecular Weight: 238.289
• Mol File: 741681-30-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R)-2-[(phenylmethylene)amino]-2-phenylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-[(phenylmethylene)amino]-2-phenylacetamide(741681-30-1)
• EPA Substance Registry System: (R)-2-[(phenylmethylene)amino]-2-phenylacetamide(741681-30-1)

Safety Data

• Hazardous Substances Data: 741681-30-1(Hazardous Substances Data)

Upstream product

• 700-63-0 (R)-phenylglycine amide 
• 100-52-7 benzaldehyde 

Downstream Products

• 386747-26-8 (R)-2-Phenyl-2-((R)-1-phenyl-but-3-enylamino)-acetamide 
• 893395-89-6 (R)-3-([(R)-2-amino-2-oxo-1-phenylethyl]amino)-3-phenylpropionic acid ethyl ester hydrochloride 
• 569671-27-8 Phenyl-((R)-1-phenyl-but-3-enylamino)-acetonitrile 
• 115224-13-0 (R)-4-amino-4-phenyl-1-butene 
• 4383-23-7 (S)-1-phenylbut-3-en-1-amine 
• 2941-19-7 (R)-1-phenylbutylamine 
• 104-51-8 1-butylbenzene 
• 949146-91-2 (2R)-2-(benzylamino)-2-phenylacetamide 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF CHIRAL AMINES

The invention relates to a process for the preparation of a chiral amine, whereby a ketone or aldehyde is contacted with an enantiomerically enriched phenylglycine amide to give an imine, whereby the imine is subsequently contacted with a Reformatsky reagent and the formed compound is subsequently converted into a chiral amine by means of hydrogenolysis, oxidation or a retro Strecker method.

Diastereoselective addition of allylzinc bromide to imines derived from (R)-phenylglycine amide

equation presented The highly diastereoselective addition of allylzinc bromide to imines derived from (R)-phenylglycine amide is reported. Homoallylamines with high enantiomeric purity are obtained from the adducts in three steps on removal of the chiral