388061-72-1

Basic information

• Product Name: 3-(2-(triMethylsilyl)ethynyl)phenol
• Synonyms: 3-(2-(triMethylsilyl)ethynyl)phenol;Phenol, 3-[2-(triMethylsilyl)ethynyl]-;3-((TriMethylsilyl)ethynyl)phenol
• CAS NO: 388061-72-1
• Molecular Formula: C₁₁H₁₄OSi
• Molecular Weight: 190.31376
• Mol File: 388061-72-1.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 260.6±32.0 °C(Predicted)
• Appearance: /
• Density: 1.01±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 9.67±0.10(Predicted)
• CAS DataBase Reference: 3-(2-(triMethylsilyl)ethynyl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-(triMethylsilyl)ethynyl)phenol(388061-72-1)
• EPA Substance Registry System: 3-(2-(triMethylsilyl)ethynyl)phenol(388061-72-1)

Safety Data

• Hazardous Substances Data: 388061-72-1(Hazardous Substances Data)

Usage

General Description

3-(2-(trimethylsilyl)ethynyl)phenol is a chemical compound with the molecular formula C12H16OSi. It is a derivative of phenol and contains a silyl-ethynyl functional group. 3-(2-(triMethylsilyl)ethynyl)phenol is commonly used in the synthesis of pharmaceuticals and agrochemicals due to its wide range of applications. It is also used as a reagent in various chemical reactions, and its silyl-ethynyl group allows it to participate in cross-coupling reactions and other organic transformations. Additionally, it is utilized in the development of materials such as polymers and coatings due to its unique chemical properties and reactivity. Overall, 3-(2-(trimethylsilyl)ethynyl)phenol is a versatile and important compound in the field of organic chemistry and materials science.

Upstream product

• 626-02-8 3-Iodophenol 
• 1066-54-2 trimethylsilylacetylene 
• 591-20-8 3-Bromophenol 

Downstream Products

• 10401-11-3 3-hydroxy phenylacetylene 
• 942202-08-6 1,4-bis(3-hydroxyphenyl)-1H-1,2,3-triazole 
• 1078733-86-4 3,3'-(thiophene-2,5-diyl)diphenol 
• 146846-56-2 3-(4-(3-hydroxyphenyl)buta-1,3-diynyl)phenol 
• 1312798-80-3 1,4-bis(3-glycidyloxyphenyl)-1H-1,2,3-triazole 
• 1312798-82-5 1,4-bis(3-cyanooxyphenyl)-1H-1,2,3-triazole 
• 10401-10-2 3-(3-hydroxyphenyl)-2-propynoic acid 
• 111731-38-5 1-phenyl-2-(m-hydroxyphenyl)acetylene 
• 937593-04-9 1-(3-bromophenyl)-2-(3-hydroxyphenyl)ethane-1,2-dione 
• 1042149-70-1 C₁₇H₁₆O₆ 
• 63192-57-4 (1,2-bis(3-hydroxyphenyl)ethane-1,2-dione) 

Relevant articles and documents

ANTIBACTERIAL ADJUVANTS AND APPLICATIONS THEREOF

In one aspect, compounds and methods are described herein for treating gram negative bacteria having resistance to cationic antimicrobial peptides. In some embodiments, for example, compounds of formula I are provided. In another aspect, a treatment for a gram negative bacterial infection comprises a cationic antimicrobial protein (CAP) in conjunction with a compound of formula I.

Design and synthesis of cyclic acylguanidines as BACE1 inhibitors

Based on the lead compound 1 reported in literature, a series of novel BACE1 inhibitors were designed and synthesized, among which compound 11 exhibited a 14-fold improvement in potency over the lead compound 1. This represents a good lead for the discovery of more promising BACE1 inhibitors for the potential treatment of AD.

HALOGEN-FREE FLAME RETARDING MATERIALS BASED ON BISPHENOL TRIAZOLE RESINS AND POLYMERS

The invention provides halogen-free, bisphenol triazole resins and polymers having exceptional flame retarding properties, related compositions and methods of making and use thereof.