3884-02-4 Usage
General Description
L-Histidine, N-[N-[N-[(phenylmethoxy)carbonyl]glycyl]glycyl]-, methyl ester is a chemical compound that is a derivative of the amino acid histidine. L-Histidine, N-[N-[N-[(phenylmethoxy)carbonyl]glycyl]glycyl]-, methyl
ester is a methyl ester, which means it has a methyl group attached to the carboxyl group of the amino acid. It also contains glycine and phenylmethoxycarbonyl groups, which are often used in the synthesis of peptide compounds. This chemical may be used in research and in the development of pharmaceuticals, particularly in the field of peptide chemistry and drug design. It is important to handle this compound with care and follow appropriate safety protocols, as it may have potential health hazards if not used properly.
Check Digit Verification of cas no
The CAS Registry Mumber 3884-02-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,8,8 and 4 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 3884-02:
(6*3)+(5*8)+(4*8)+(3*4)+(2*0)+(1*2)=104
104 % 10 = 4
So 3884-02-4 is a valid CAS Registry Number.
3884-02-4Relevant articles and documents
Synthesis and antitumor properties of an anthraquinone bisubstituted by the copper chelating peptide Gly-Gly-L-His
Morier-Teissier,Boitte,Helbecque,Bernier,Pommery,Duvalet,Fournier,Hecquet,Catteau,Henichart
, p. 2084 - 2090 (2007/10/02)
A new molecule 4 [(GGH-DAE)2DHQ] associating the 1,4,5,8- tetrahydroxyanthraquinone ring (DHQ) of the antitumor drug mitoxantrone (2), two diaminoethylene chains (DAE), and the metal-chelating peptide Gly-Gly- His (GGH) has been synthesized. Such a molecule presents characteristics able to induce antitumor activity: compound 4 intercalates into DNA as measured by ΔT(m), fluorescence quenching, and viscometry; ESR studies demonstrate that several types of Cu complexes are formed depending on pH; and the production of free radicals, as evidenced by spin-trapping, is enhanced by 4. In vitro, in leukemia cells L1210 and mammary cells MCF7, 4 is slightly less cytostatic than mitoxantrone, but substantially less toxic. In vivo, in leukemia P388 on mice, a T/C value of 230 is obtained at 25 mg/kg, higher than the one of mitoxantrone, which is toxic at the same dose.
